A UK randomized, single-blind, controlled trial of 135 otherwise healthy participants with periodontitis showed that intensive periodontal treatment (IPT) improved vascular outcomes beyond endothelial function. Participants were randomized to IPT (scaling, root planning, and corrective surgery if needed) or control periodontal treatment (CPT: supra-gingival scaling and polishing) and followed for […]
A prospective cohort study involving 12,134 Chinese adults examined the link between intake of refined carbohydrates, staple foods, and the risk of metabolic dysfunction-associated steatotic liver disease (MASLD). Over a median follow-up of 4.32 years, 4,447 new MASLD cases were identified. Higher total refined carbohydrate intake was associated with increased […]
A randomized controlled crossover trial in England examined the impact of ultraprocessed food (UPF) consumption on weight loss within the framework of national dietary guidelines. Fifty-five adults (BMI 25–40, with habitual UPF intake ≥50% of daily calories) were assigned two 8-week ad libitum diets based on the UK Eatwell Guide: […]
A Kenya panel study suggested that drinking water sodium-chloride may elevate blood pressure (BP) and kidney disease risk, even in populations with minimal traditional chronic disease risk factors. The two-year panel study was conducted in 2022 and 2023 among 327 Daasanach adults over 18 years old in northern Kenya (434 […]
A U.S. randomized clinical trial found that 4:3 intermittent fasting (IMF) led to slightly greater weight loss than daily caloric restriction (DCR) in adults with overweight or obesity. The study included 165 participants (mean age: 42; mean BMI: 34.1 kg/m²; 73.9% female), randomly assigned to either 4:3 IMF (n=84) or […]
A Danish nationwide cohort study provided real world evidence that both glucagon-like peptide 1 receptor agonists (GLP1-RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT-2is) were associated with reduced rates of 3-point major adverse cardiovascular events (3P-MACE) and hospitalization for heart failure (HHF) compared to dipeptidyl peptidase 4 inhibitors (DPP-4is). Compared to […]
A systematic review and meta-analysis of placebo-controlled randomized trials showed that there is moderate certainty evidence that non-steroidal anti-inflammatory drugs (NSAIDs) are efficacious for acute low back pain, and that exercise, spinal manipulative therapy, taping, antidepressants, and transient receptor potential vanilloid 1 (TRPV1) agonists are efficacious for chronic low back […]
A US cohort study indicated that statin use may reduce the risks of hepatocellular carcinoma (HCC) and progression of chronic liver disease (CLD). The study included 16 501 CLD patients (mean age, 59.7 years, females 40.9%), with 3610 statin users and 12 891 nonusers. Compared with nonusers, statin users exhibited a significantly […]
A prospective US population-based cohort study suggested that higher intake of butter was associated with increased mortality, while higher intake of plant-based oils was associated with lower mortality. Substituting butter with plant-based oils may prevent premature deaths. There were 221 054 adults with mean age at baseline of 36.1 ~ 56.3 […]
Cognitive Behavioral Therapy (CBT) has been shown to be effective in managing Irritable Bowel Syndrome (IBS) by addressing the connection between the gut and the brain. Following are some available programs: Mahana IBS (FDA-Approved): A clinically validated, prescription 3-month digital therapy program designed to reduce the severity of IBS symptoms. […]