Greater Adherence to the MIND Diet Linked to Slower Brain Aging   Recently updated !

A prospective US study suggests that greater adherence to the Mediterranean–Dietary Approaches to Stop Hypertension Diet Intervention for Neurodegenerative Delay (MIND) diet was associated with slower structural brain aging, including reduced gray matter loss and slower enlargement of brain ventricles over time. In the analysis of 1,647 middle-aged and older […]

Elevated Aldosterone-Renin Ratio Tied to Atrial Fibrillation and Stroke in Older Adults   Recently updated !

A prospective US cohort study leveraging data from 3,477 participants (mean age 74.8 years; 61.5% female) in the Atherosclerosis Risk in Communities (ARIC) study has found that higher aldosterone-renin ratio (ARR) is independently associated with increased cardiovascular risk over nearly a decade of follow-up. Researchers measured serum aldosterone and renin […]

Multivitamins May Slow Biological Aging   Recently updated !

A recent study suggests that daily multivitamin-mineral supplements could slightly slow the biological aging process in older adults, though the effect size is modest and requires further investigation. As part of the COSMOS trial, researchers analyzed data from 958 participants over two years using advanced “epigenetic clocks”—DNA methylation measures that […]

SGLT2 Inhibitors Tied to Lower Risk in Patients with Diabetes and Cirrhosis

A rigorous cohort study utilizing Taiwan’s National Health Insurance Database provides robust evidence that SGLT2 inhibitors offer superior multi-organ protection for the complex population of patients with both type 2 diabetes and liver cirrhosis. Among 24,259 adults (average age 64.7 years; 33.9% female) followed for a median of 2.3 years, […]

Lobar and Mixed Cerebral Microbleeds Linked to Increased Dementia Risk

A new study investigating the link between cerebral microbleeds (CMBs) and dementia has found that the location and pattern of these brain lesions are critical to assessing risk. Analyzing data from over 1,500 participants in the ARIC-Neurocognitive Study, researchers classified individuals based on their CMB patterns—lobar, subcortical, or mixed—and tracked […]

DASH Diet Best for Long-Term Brain Health

A comprehensive prospective study tracking over 159,000 adults for up to three decades has provided compelling evidence that multiple healthy dietary patterns protect cognitive function, with the DASH diet demonstrating the most powerful effects. Researchers simultaneously evaluated six dietary approaches—including the Mediterranean-style AHEI-2010, plant-based hPDI, environmentally-focused PHDI, and diets targeting […]

Intermittent Fasting Shows No Clear Advantage Over Traditional Diets for Weight Loss

A comprehensive new Cochrane review of 22 studies involving nearly 2,000 participants over six months to one year has found that intermittent fasting may offer little to no significant benefit over standard dietary advice for weight loss in people with overweight or obesity. When compared to regular, calorie-restricted diet plans, […]

Healthy Dietary Patterns Linked to Better Life Expectancy

A large-scale study involving 103,649 UK Biobank participants has revealed that adhering to healthy dietary patterns is significantly associated with lower mortality rates and a longer lifespan. Over a median follow-up of 10.6 years, researchers found that five specific diets—the Alternate Healthy Eating Index-2010, Alternate Mediterranean Diet (AMED), healthful Plant-based […]

Statin Adverse Effects Analysis: Separating Signal from Noise

To address uncertainties in statin safety profiles, which are often based on observational data susceptible to bias, researchers conducted a definitive meta-analysis of individual participant data from major double-blind, randomized controlled trials. The study first identified all undesirable effects listed in the official Summaries of Product Characteristics (SmPCs) for five […]

Early Time-of-Day Immunotherapy Shows Survival Benefit in Lung Cancer Trial

In a Chinese phase 3 trial (LungTIME-C01) involving 210 patients with advanced non-small cell lung cancer, administering anti-PD-1 immunotherapy before 3:00 PM nearly doubled progression-free survival (11.3 vs. 5.7 months) and significantly improved overall survival (28.0 vs. 16.8 months) compared to later infusions. This early time-of-day treatment was linked to […]