Resistance Training Significantly Lowers CVD Risk in Women

Women who consistently performed resistance training had a substantially lower risk of major cardiovascular disease (CVD), particularly heart attacks, according to a prospective study involving more than 117,000 U.S. women followed for an average of 14.5 years. Compared with women who did no resistance training, those engaging in at least […]


Intensive Lifestyle Intervention Reduces Long-Term Multimorbidity in Prediabetes

US Adults with prediabetes who participated in an intensive lifestyle intervention had a significantly lower risk of developing multiple chronic diseases over 25 years, while metformin did not provide a similar benefit. This long-term follow-up of the Diabetes Prevention Program (DPP) and Diabetes Prevention Program Outcomes Study (DPPOS) included 1,173 […]


Recombinant Shingles Vaccine Linked to Lower Dementia Risk

A U.S. study found that receiving the recombinant herpes zoster vaccine (RZV, shingles vaccine) was associated with a significantly lower risk of developing dementia among older adults admitted to skilled-nursing facilities. Researchers analyzed data from 509,926 Medicare beneficiaries aged 66 years or older who had no prior dementia diagnosis and […]


Sugar-Sweetened Beverages Linked to Higher Risk of Liver Cancer Subtypes

A pooled analysis of 11 prospective cohort studies involving more than 1.5 million adults found that higher consumption of sugar-sweetened beverages (SSBs) was associated with an increased risk of both hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), whereas artificially sweetened beverages (ASBs) were not associated with liver cancer risk. Researchers […]


Vitamin K2 (MK-7) May Slow Coronary Artery Calcification Progression

A Dutch randomized clinical trial found that two years of vitamin K2 (menaquinone-7, MK-7) supplementation significantly slowed the progression of coronary artery calcification (CAC) in patients with symptomatic coronary artery disease (CAD) compared with placebo. In the VitaK-CAC study, 180 patients with existing coronary calcification were randomized to receive either […]


Rising ADHD and Autism Diagnoses May Reflect Broader Diagnostic Criteria

A Danish population-based cohort study found that individuals diagnosed with attention-deficit/hyperactivity disorder (ADHD) or autism spectrum disorder (ASD) in more recent years carried lower average genetic risk scores for these conditions and related psychiatric traits than those diagnosed earlier, suggesting that the rising prevalence of ADHD and ASD is more […]


Hyperglycosylation Maybe a Key Driver of Alzheimer’s Disease Progression

A new study identifies brain hyperglycosylation—an excessive buildup of sugar-containing glycans on proteins—as a pathological driver of Alzheimer’s disease (AD), revealing a promising new target for treatment. By integrating spatial metabolomics, lipidomics, glycomics, and advanced isotopic tracing techniques in transgenic AD mouse models and post-mortem human brain samples, researchers found […]


2026 Key Recommendations for Preventing and Managing Cardiovascular-Kidney-Metabolic Syndrome

Preventing progression and promoting regression of cardiovascular-kidney-metabolic (CKM) syndrome requires early staging, comprehensive risk assessment, management of risk factors, and use of evidence-based therapies across the life course. CKM syndrome staging is recommended for youths and adults to guide treatment and reduce cardiovascular and kidney complications. Individuals with CKM stages […]


Low Lipoprotein(a) Levels Linked to Higher Diabetes Risk

An analysis from the FOURIER trial found that among patients with established atherosclerotic cardiovascular disease, lower lipoprotein(a) [Lp(a)] concentrations were associated with a higher prevalence of diabetes at baseline and a greater risk of developing diabetes during follow-up, while showing no increased risk of most other major adverse safety outcomes. […]