Long-term follow-up of two randomized lifestyle intervention trials found that reducing visceral fat—not simply losing weight—was strongly associated with sustained cardiometabolic health benefits, and every 10% reduction in visceral fat lowered the future risk of type 2 diabetes by 28%. Researchers followed 366 participants from the 18-month CENTRAL and DIRECT-PLUS […]
A comprehensive systematic review and meta-analysis involving 69 randomized controlled trials and 153,902 adults found that calcium supplements, vitamin D supplements, or their combination offer little to no clinically meaningful benefit in preventing fractures or falls in adults not taking osteoporosis medications. Most participants were community-dwelling individuals (87%) and were […]
A new clinical practice guideline from the American Academy of Sleep Medicine indicates that cognitive behavioral therapy for insomnia (CBT-I) alone remains the most effective first-line treatment for chronic insomnia, while adding medication may offer modest benefits for select outcomes such as total sleep time. The guideline is supported by […]
A prospective US study suggests that greater adherence to the Mediterranean–Dietary Approaches to Stop Hypertension Diet Intervention for Neurodegenerative Delay (MIND) diet was associated with slower structural brain aging, including reduced gray matter loss and slower enlargement of brain ventricles over time. In the analysis of 1,647 middle-aged and older […]
A comprehensive prospective study tracking over 159,000 adults for up to three decades has provided compelling evidence that multiple healthy dietary patterns protect cognitive function, with the DASH diet demonstrating the most powerful effects. Researchers simultaneously evaluated six dietary approaches—including the Mediterranean-style AHEI-2010, plant-based hPDI, environmentally-focused PHDI, and diets targeting […]
A comprehensive new Cochrane review of 22 studies involving nearly 2,000 participants over six months to one year has found that intermittent fasting may offer little to no significant benefit over standard dietary advice for weight loss in people with overweight or obesity. When compared to regular, calorie-restricted diet plans, […]
A large-scale study involving 103,649 UK Biobank participants has revealed that adhering to healthy dietary patterns is significantly associated with lower mortality rates and a longer lifespan. Over a median follow-up of 10.6 years, researchers found that five specific diets—the Alternate Healthy Eating Index-2010, Alternate Mediterranean Diet (AMED), healthful Plant-based […]
Released in early 2026, the latest U.S. Dietary Guidelines champion a “real food” approach, advising Americans to prioritize whole foods like vegetables, fruits, proteins, and healthy fats while sharply limiting ultra-processed items, added sugars, and artificial additives. This update introduces significant shifts, including a higher daily protein recommendation, a move […]
Even moderate alcohol consumption was consistently linked to a higher risk of multiple cancers, with clear dose–response relationships showing that risk rises with greater frequency and quantity of drinking. In this systematic review of 62 U.S.-based studies, alcohol use was most strongly associated with increased risks of breast, colorectal, and […]
A growing body of evidence shows that ultra-processed foods are displacing traditional, whole-food diets worldwide and driving major diet-related chronic diseases. Drawing on decades of dietary surveys, global sales data, cohort studies, randomized trials, and mechanistic research, this first paper in a three-part Lancet Series reports that ultra-processed foods have […]