Global Study of Stroke Risk Factors   Recently updated !

A study revealed that stroke remains a major global health challenge, influenced by numerous risk factors that vary across regions and populations. The study analyzed stroke-related mortality from 1990 to 2021 using Global Burden of Disease 2021 data, focusing on three primary stroke subtypes: ischemic stroke, intracerebral hemorrhage, and subarachnoid […]

Antidepressants Effective and Safe in Older Adults with Anxiety   Recently updated !

A systematic review and meta-analysis evaluated randomized controlled trials on pharmacological treatments for anxiety in adults aged 60 and older, identifying 19 eligible studies with 2,336 participants (68% women). The primary outcomes included reductions in anxiety symptoms, treatment response, or remission. Antidepressants were found to be more effective than placebo […]

Geographical Variation in Lipoprotein (a) Levels Among CHD Patients

A global study suggested that most patients with coronary heart disease (CHD) have Lipoprotein (a) [Lp(a)] levels below risk-enhancing thresholds with wide geographical variations. The study assessed Lp(a) levels in 3,928 CHD patients across 13 countries in six World Health Organization regions. Median Lp(a) level was 32 nmol/L, with 17.6% […]

The Science and Skepticism around Seed Oils

A recent article explored the science and skepticism surrounding seed oils. These oils—extracted from sources such as soy, canola, sunflower, and corn—are rich in unsaturated fats, particularly polyunsaturated fats (PUFAs) like omega-6 linoleic acid. A substantial body of evidence supports the health benefits of replacing saturated fats with PUFAs. However, […]

Bedtime Antihypertensive Comparable to Morning Use

A Canadian study of adults with high blood pressure (BP) found no difference in health outcomes between taking BP medications in the morning versus at bedtime. A total of 3,357 adult patients with high BP (56.4% female; median age, 67 years; 53.7% on monotherapy) were randomly assigned to take their […]

Obicetrapib Effective and Safe in Improving Lipids

Two randomized, controlled trials evaluated the efficacy and safety of obicetrapib, an oral cholesteryl ester transfer protein (CETP) inhibitor, in lowering low-density lipoprotein (LDL) cholesterol in patients at high risk for atherosclerotic cardiovascular disease (ASCVD). Both trials show that obicetrapib is effective in reducing LDL cholesterol, with enhanced efficacy when […]

Hyperlipidemias and Inflammation Independently and Synergistically Raise CVD Risk

A UK longitudinal associations study revealed that hyperlipidemias and inflammation independently and together raise the risk of serious cardiovascular diseases (CVD). The risk is more closely tied to the actual blood levels of these markers than to the use or not of cholesterol-lowering medication. Data were from 322,922 participants (55.9% […]

Ultraprocessed Food Consumption and Early Death

A study shows that eating a lot of highly processed foods is likely causing a significant number of early deaths around the world. First, a dose–response meta-analysis of observational cohort studies was performed to assess the association between ultraprocessed food consumption and all-cause mortality. Then, an estimation was made for […]

Dose Response of Physical Activity in CVD and Mortality

Two recent studies highlight the importance of physical activity volume and intensity in reducing cardiovascular disease (CVD) risk and improving longevity. The first study analyzed data from over 24,000 middle-aged and older non-exercisers in the UK Biobank, examining the effects of incidental physical activity (IPA)—unstructured daily movement outside formal exercise—on […]

Faster Walking Pace May Reduce Risk of Cardiac Arrhythmias

A prospective UK cohort study found that both self-reported average or brisk walking pace and accelerometer-measured time spent walking at moderate or brisk pace were associated with a lower risk of cardiac arrhythmias. These associations were partially mediated by metabolic and inflammatory factors. Self-reported walking pace data were available for […]