Maintaining optimal vascular health in midlife was associated with up to 12.6 additional years of life free from dementia between ages 55 and 95. The prospective analysis of 12,409 participants from the US Atherosclerosis Risk in Communities (ARIC) study followed for a median of 26.3 years, evaluated three major midlife […]
A US community-based study found that middle-aged adults with blood biomarkers indicating Alzheimer’s disease neuropathology already showed worse cognition and faster cognitive decline years before dementia diagnosis. Researchers analyzed 1,350 participants from the Coronary Artery Risk Development in Young Adults (CARDIA) study who underwent plasma biomarker testing at year 35 […]
Higher physical activity in midlife and late life—but not early adulthood—is associated with a significantly lower risk of both all-cause and Alzheimer disease dementia. In this prospective analysis from the US Framingham Heart Study Offspring cohort, 1526 early-adult, 1943 midlife, and 885 late-life participants were followed for up to 37 […]