A US community-based study found that middle-aged adults with blood biomarkers indicating Alzheimer’s disease neuropathology already showed worse cognition and faster cognitive decline years before dementia diagnosis. Researchers analyzed 1,350 participants from the Coronary Artery Risk Development in Young Adults (CARDIA) study who underwent plasma biomarker testing at year 35 […]
Anemia was associated with higher levels of Alzheimer disease (AD) blood biomarkers and a markedly increased long-term risk of dementia, with the highest risk observed when low hemoglobin coexisted with elevated neurodegenerative markers. In a population-based cohort from the Swedish National Study on Aging and Care in Kungsholmen, 2,282 dementia-free […]
A US study showed that intensive systolic blood pressure (SBP) lowering increased hs-cTnT (high-sensitivity cardiac troponin T), mediated by reduced kidney filtration; and decreased NT-proBNP (N-terminal pro-B-type natriuretic peptide), mediated by the drop in SBP. The observed changes in hs-cTnT and NT-proBNP levels with intensive SBP lowering were associated with […]