A comprehensive new Cochrane review of 22 studies involving nearly 2,000 participants over six months to one year has found that intermittent fasting may offer little to no significant benefit over standard dietary advice for weight loss in people with overweight or obesity. When compared to regular, calorie-restricted diet plans, […]
Released in early 2026, the latest U.S. Dietary Guidelines champion a “real food” approach, advising Americans to prioritize whole foods like vegetables, fruits, proteins, and healthy fats while sharply limiting ultra-processed items, added sugars, and artificial additives. This update introduces significant shifts, including a higher daily protein recommendation, a move […]
Findings of a UK clinical trial support the use of the Mediterranean diet (MD) as a first-line therapy for irritable bowel syndrome (IBS). A total of 139 adults with IBS (mean age 40.4 years; 80% women) from across the UK were randomized to follow either the MD (n = 68) […]
The British Dietetic Association has developed the first comprehensive evidence-based dietary guidelines for the management of chronic constipation in adults. Four systematic reviews and meta-analyses encompassing 75 randomized controlled trials informed 59 recommendation statements, developed through the GRADE framework and Delphi consensus among a multidisciplinary Guideline Steering Committee. The recommendations […]
A US cohort study revealed genotype-dependent metabolic signatures of cognitive health and support precision nutrition approaches, such as Mediterranean diet for Alzheimer’s disease and related dementias (AD/ADRD) prevention. The study analyzed genetic, plasma metabolomic, and dietary data from 4,215 women and 1,490 men in prospective cohorts. The associations between 57 […]
A US randomized, 4-period crossover feeding study revealed that sodium reduction, especially when combined with a Dietary Approaches to Stop Hypertension (DASH)-style diet optimized for diabetes (DASH4D), can significantly lower blood pressure (BP) in patients with type 2 diabetes (T2D) and high BP, even among those already using multiple antihypertensive […]
A Spanish secondary prevention study suggested that Mediterranean diet might reduce neutrophil levels and slow the progression of atherosclerosis and was superior to a low-fat diet in preventing major events of coronary heart disease (CHD). A total of 1002 CHD patients were randomly assigned to follow either a low-fat diet […]
An ongoing UK national prospective program shows remission of type 2 diabetes (T2D) outside of research settings, through at-scale service delivery. Between Sept 1, 2020, and Dec 31, 2022, 7540 people (aged 18–65 years diagnosed with T2D within the last 6 years) were referred, 1740 started total diet replacement (TDR) […]
A multilipid score (MLS), reflecting the effects of replacing saturated fat with unsaturated fat on 45 lipid metabolite concentrations, was associated with significantly lower risk of cardiovascular diseases (CVD) and type 2 diabetes (T2D). The MLS was based on lipidomics data from a randomized controlled dietary intervention trial, replacing specific […]
A prospective UK population-based cohort study suggests that higher adherence to the EAT-Lancet diet is associated with lower risks of incident depression, anxiety and their co-occurrence. The study included 180,446 participants (mean age 56.2, male 46.45%) with 11.62 years of follow-up. The diet largely consists of vegetables, fruits, whole grains, […]