Anxiety


Primary Care Approaches to Anxiety: CBT and SSRIs/SNRIs Lead Effective Treatment

Anxiety disorders are common yet often underrecognized in primary care, but a review shows that cognitive-behavioral therapy (CBT), selective serotonin and serotonin-norepinephrine reuptake inhibitors (SSRIs/SNRIs), and collaborative care models can substantially improve outcomes. Current recommendations support anxiety screening for adults younger than 65 years, with assessment including symptom questionnaires, clinical […]


Smartphone-Based Digital CBT Produces Large and Sustained Benefits for GAD

In a fully remote US randomized clinical trial of 351 adults with generalized anxiety disorder (GAD), smartphone-delivered digital cognitive behavioral therapy (DCBT) produced significantly greater symptom improvement and higher remission rates than an active psychoeducation control, with benefits sustained through 24 weeks. The DCBT mobile application (DaylightRx) for GAD delivered […]


Mental Wellbeing Mitigated IBS Risk

Better mental wellbeing substantially reduces the risk of developing irritable bowel syndrome (IBS), with effects that are independent of genetic predisposition and partly mediated through lower depression and anxiety. In this prospective UK Biobank cohort of 75,842 IBS-free participants followed for 12.4 years, 1,400 incident IBS cases occurred, and higher […]


Antidepressants Effective and Safe in Older Adults with Anxiety

A systematic review and meta-analysis evaluated randomized controlled trials on pharmacological treatments for anxiety in adults aged 60 and older, identifying 19 eligible studies with 2,336 participants (68% women). The primary outcomes included reductions in anxiety symptoms, treatment response, or remission. Antidepressants were found to be more effective than placebo […]


Mindfulness-Based Stress Reduction on Par with Escitalopram for Anxiety Disorders

Both clinician-rated and patient-reported outcomes suggested that mindfulness-based stress reduction (MBSR) was well-tolerated with comparable effectiveness to the first-line medication escitalopram for patients with anxiety disorders in a US randomized clinical trial. The trial included 276 participants (women 75%, men 25%; mean age 33 years; Asian 19%, Black 15%, Hispanic […]


Healthy and Sustainable Diet Beneficial for the Prevention of Depression and Anxiety

A prospective UK population-based cohort study suggests that higher adherence to the EAT-Lancet diet is associated with lower risks of incident depression, anxiety and their co-occurrence. The study included 180,446 participants (mean age 56.2, male 46.45%) with 11.62 years of follow-up. The diet largely consists of vegetables, fruits, whole grains, […]