A Danish nationwide cohort study provided real world evidence that both glucagon-like peptide 1 receptor agonists (GLP1-RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT-2is) were associated with reduced rates of 3-point major adverse cardiovascular events (3P-MACE) and hospitalization for heart failure (HHF) compared to dipeptidyl peptidase 4 inhibitors (DPP-4is). Compared to […]
A US cohort study suggests that carotid artery plaque (CAP) becomes very common with increasing age among individuals without clinical atherosclerotic cardiovascular disease (ASCVD), and the association of CAP with incident ASCVD events was stronger in younger ages, especially among women. A total of 5689 participants with complete data were […]
A prospective US population-based cohort study suggested that higher intake of butter was associated with increased mortality, while higher intake of plant-based oils was associated with lower mortality. Substituting butter with plant-based oils may prevent premature deaths. There were 221 054 adults with mean age at baseline of 36.1 ~ 56.3 […]
A prespecified subgroup analysis of a Chinese randomized clinical trial suggested that salt substitution significantly reduced the risks of stroke recurrence and death. The analysis included 15 249 patients with stroke (mean age, 64.1 years; female 45.9%; male 54.1%) from an open-label, cluster randomized clinical trial. Patients were assigned to […]
A US prospective cohort analysis suggested that supine high blood pressure (BP) regardless of seated high BP was associated with a higher risk of CVD and mortality than seated high BP alone. The analysis used data from 11 369 participants without known CVD (female 55.7%, male 44.3%; Black 25.1%, White 74.9%; […]
A Spanish secondary prevention study suggested that Mediterranean diet might reduce neutrophil levels and slow the progression of atherosclerosis and was superior to a low-fat diet in preventing major events of coronary heart disease (CHD). A total of 1002 CHD patients were randomly assigned to follow either a low-fat diet […]
Top 10 key takeaway points of the report of the American College of Cardiology Solution Set Oversight Committee for the diagnosis and management of myocarditis: 1. Be aware of the 3 classic presentations of myocarditis: chest pain, heart failure/shock, and/or symptoms related to arrhythmia (eg, presyncope or syncope), especially in […]
A UK device-based prospective study suggested that irregular sleep was associated with higher risk of major adverse cardiovascular events (MACE), regardless of whether individuals met sleep duration recommendations or not. The study included 72 269 individuals aged 40–79 years and followed for 7.8 years, without a previous history of MACE and […]
A Chinese parallel design, randomized clinical trial showed that the incidence of major cardiovascular events among patients with type 2 diabetes (T2D) was significantly lower with intensive treatment targeting a systolic blood pressure (SBP) of less than 120 mm Hg than with standard treatment targeting a SBP of less than […]
A study comparing UK adults conceived just before or after sugar rationing ended found that early-life sugar rationing reduced risk of type 2 diabetes (T2D) and high blood pressure (HBP). The sugar rationing ended in September 1953 restricted sugar intake to levels within current dietary guidelines, but consumption nearly doubled […]