A randomized trial found that a combined low-energy diet (800–900 kcal/day) and structured exercise program induced type 2 diabetes remission in 54% of adults with early-onset type 2 diabetes (≤45 years), compared with only 4% receiving usual care at 24 weeks. The open-label trial included 96 adults aged 18–45 years […]
Heart failure (HF) affects nearly 1 in 4 Americans over their lifetime, and its growing prevalence, rising mortality, widening disparities, and persistent undertreatment have made it an increasingly urgent public health crisis. About one-third of U.S. adults without symptomatic HF are already at risk (Stage A), while another 24–34% have […]
Alcohol consumption was independently associated with a substantially higher risk of hepatocellular carcinoma (HCC) among patients with chronic hepatitis B (CHB), regardless of cirrhosis status. In this study of 1,010 CHB patients followed for a total of 3,684 person-years, 129 (12.77%) developed HCC. Compared with patients without HCC, those who […]
Consuming sweets and simple sugars during antibiotic treatment was associated with greater gut microbiome disruption, including reduced microbial diversity and expansion of the pathobiont Enterococcus. In this study, researchers precisely tracked 9,419 meals consumed by 173 patients undergoing haematopoietic cell transplantation and analyzed longitudinal microbiome changes in 158 patients with […]