A Chinese nationwide study of 273,921 patients hospitalized with heart failure (HF) found a U-shaped association between left ventricular end-diastolic diameter (LVEDD) and mortality, with both abnormally small and abnormally large left ventricles independently associated with higher all-cause mortality. Using data from the Chinese Cardiovascular Association Database–Heart Failure Center Registry, […]
A systematic review and meta-analysis found that intravenous thrombolysis (IVT) given 4.5 hours or more after acute ischemic stroke onset was associated with better functional outcomes, although it increased the risk of symptomatic intracerebral hemorrhage (ICH). The analysis included 14 randomized clinical trials involving 4,174 patients comparing IVT with placebo […]
Waist circumference (WC) and waist-to-hip ratio (WHR) identified important differences in cardiovascular disease (CVD) risk that were not captured by conventional BMI categories, suggesting that central adiposity can reclassify CVD risk across normal weight, overweight, and obesity and provide additional diagnostic and prognostic information. The US Cross-Cohort Collaboration study included […]