Monthly Archives: December 2023

Genetic Risks in Sodium and Potassium Informative to High BP Interventions

This entry was posted in Cardiovascular Diseases and tagged Genetics High Blood Pressure Sodium and Potassium on

A cross-sectional, observational study of 2 genotyped cohorts in Australia and UK suggested that sodium was associated with larger hypertensive effects for individuals with higher blood pressure (BP) genetic risk in pathways related to sodium and potassium biology. Both genetic risk and urinary electrolytes independently correlated with BP in the […]

Irregular Sleep Linked to Dementia and Brain Volume

This entry was posted in Health Mental Disorders and tagged Brain Volume Dementia Sleep Regularity on

A UK cohort study suggested that irregular sleep may represent a novel dementia risk factor. A random selection of 88,094 individuals (mean age 62 years, 56% women, and median sleep regularity index [SRI] 60) from a UK cohort was done between February 2013 and December 2015. The SRI was calculated […]

Efficacy and Safety of Bempedoic Acid

This entry was posted in Cardiovascular Diseases and tagged Bempedoic Acid Efficacy Safety on

In the prespecified analysis of a randomized, double-blind, placebo-controlled trial, bempedoic acid reduces LDL cholesterol, high-sensitivity C-reactive protein, and risk of cardiovascular events among those with baseline diabetes, prediabetes, or normoglycemia, with or without cardiovascular disease at baseline. Between Dec 22, 2016, and Nov 7, 2022, 13 970 patients who were […]

Healthy Vegan Bettered Healthy Omnivorous Diet

This entry was posted in Health Uncategorized and tagged Identical Twin Pairs Omnivorous Diet Plant-Based Diets on

A US randomized clinical trial of healthy adult identical twin pairs showed that a healthy plant-based diet offers a significant protective cardiometabolic advantage compared with a healthy omnivorous diet. The open-label, parallel, dietary randomized clinical trial enrolled 22 pairs of twins (N = 44, 34 female; mean age, 39.6 years; mean body […]

Early Life BP Linked to Adult Arterial Thickening

This entry was posted in Cardiovascular Diseases and tagged Carotid Intima-Media Thickness Early Life Blood Pressure on

A Finnish randomized, infancy-onset cohort study indicated that accumulation of risk exposure to BP levels at all life stages contributed to adulthood carotid intima-media thickness (IMT). The study included 534 participants from July 1989 through January 2018 with annual BP (from age 7 months to 20 years), biennial IMT measurements […]

US 2023 AF Guideline

This entry was posted in Cardiovascular Diseases and tagged Atrial Fibrillation Guideline on

The US 2023 atrial fibrillation (AF) guideline emphasizes a rhythm control strategy and highlight the need for lifestyle and risk factor modification in addition to medical treatment. Key points including: The new proposed classification of AF by 4 stages, recognizes AF as a disease continuum that requires a variety of […]