A US longitudinal clinical-pathologic study revealed that healthy diet is associated with cognitive resilience (defined as performing better than expected given burden of neuropathology) independently of common brain pathology in older adults. The study included 569 decedents with valid dietary data, cognitive testing proximate to death, and complete autopsy data. […]
A prospective observational study indicated that a healthy sleep pattern was associated with lower risks of atrial fibrillation/flutter (AF) and bradyarrhythmia, independent of traditional risk factors, and the association of the healthy sleep pattern with the risk of AF was stronger among those with a lower genetic risk of AF. […]
Two separate studies in the US suggested that plant-based foods were associated with lower risk of cardiovascular disease (CVD) in young adults andpostmenopausal women. One study included 4,946 adults, 18 to 30-years-old at the time of enrollment from 1985 to 1986; 2,509 Black and 2,437 white adults, 54.9% women overall. […]
A UK single-arm dietary intervention study suggests that postprandial inflammation is largely driven by acute elevations in circulating triglyceride (TG). Glycoprotein acetylation (GlycA) after mixed meals may be a promising candidate biomarker for assessing the food-induced inflammatory response within typical dietary habits. The study included 1002 healthy adults aged 18–65 […]
Results from 2 prospective cohort studies of US men and women and a meta-analysis of 26 cohort studies found an inverse association between fruit and vegetable intake and mortality up to approximately 5 servings/day.The 2 prospective cohort studies included 66719 women (1984–2014) and 42016 men (1986–2014), and the dose-response meta-analysis […]
A global study concluded that a diet with a high glycemic index was associated with an increased risk of cardiovascular disease (CVD) and death. The study included 137,851 participants between the ages of 35 and 70 years living on five continents, with a median follow-up of 9.5 years. Country-specific food-frequency […]
A study shows that human sleep is synchronized with lunar phases regardless of ethnic and sociocultural background, and of the level of urbanization. The study uses wrist actimetry to show a clear synchronization of nocturnal sleep timing with the lunar cycle in participants living in environments that range from a […]
An update of the previous 2018 systematic review and meta-analysis of vitamin and mineral supplementation on cardiovascular disease (CVD) outcomes and all-cause mortality shows similar findings for preventive benefits from both folic acid and B vitamins for stroke, and an increased risk with niacin (with statin) for all-cause mortality. In […]
The 2020-2025 Dietary Guidelines for Americans are out. For the first time the Guidelines provide recommendations by life stage, from birth through older adulthood, while focusing on dietary patterns and recognizing that more than half of adults have one or more diet-related chronic diseases. The guidelines: for about the first […]
A harmonized meta-analysis concluded that longer sedentary time is associated with higher mortality in less active individuals when measured by accelerometry. About 30–40min of moderate-to-vigorous-intensity physical activity (MVPA) per day attenuate the association between sedentary time and risk of death. The analysis included 44370 middle-aged and older men and women […]