A Canadian study of healthy adults showed that leg and arm lean body mass (LBM) independently associate with internal cardiac dimensions, ventricular relaxation, and systemic vascular resistance in a sex-specific manner, predominantly in women. The study included 70 white women and men matched by age (60±12 vs 58±15 years), physical […]
The secondary analysis of a multicenter randomized clinical trial in the US and Puerto Rico showed that the beneficial effect of intensive treatment on cardiovascular and all-cause mortality did not persist after the trial, with increasing outpatient systolic blood pressure (SBP) levels in participants randomized to intensive treatment following the […]
A UK prospective cohort study suggested that decaffeinated, ground, and instant coffee, particularly at 2–3 cups/day, were consistently associated with significant reductions in incident cardiovascular disease (CVD, such as coronary heart disease, heart failure, and ischemic stroke, etc.) and mortality. Ground and instant but not decaffeinated coffee was also associated with […]
A double‐blind, randomized, sham‐controlled trial concluded that high‐resistance inspiratory muscle strength training (IMST) improves blood pressure (BP) and endothelial function in midlife/older adults with above‐normal initial systolic BP. Thirty‐six participants of 50–79 years old with systolic BP ≥120 mm Hg were randomized to high‐resistance IMST (75% maximal inspiratory pressure, 30 breaths/day, 6 days/week, n=18) or […]
A French population based prospective cohort study suggests a potential direct association between higher artificial sweetener consumption (especially aspartame, acesulfame potassium, and sucralose) and increased cardiovascular disease (CVD) risk. The study included 103 388 participants of the web-based cohort (mean age 42.2 years, 79.8% female, 904 206 person years) from 2009 to […]
An individual participant data meta-analysis concluded that most (>90%) of all reports of muscle symptoms with statin therapy were not due to the statin, although statins did cause a small proportional increase in reports of muscle pain, largely during the first year of treatment. The analysis included 19 double-blind trials […]
A multicenter, open-label, blinded–end point, randomized clinical trial in China showed that remote ischemic conditioning (RIC) was associated with better neurologic function in patients with acute moderate ischemic stroke. The trial randomly assigned 1893 patients (mean age, 65 years; women 34.1%; 93.8% completed the trial) within 48 hours after symptom […]
A meta-analyses and metaregressions concluded that the beneficial effects of salt substitutes on blood pressure and clinical outcomes were consistent and might be generalizable across diverse population subgroups worldwide. The study included 21 trials and 31 949 participants, with 19 reporting effects on blood pressure and 5 reporting effects on […]
Data from a validated and complete registration of all 2,494 acute myocardial infarction (MI) cases in Augsburg, Germany, during warm seasons (May to September) from 2001 to 2014, suggested that heat-related non-fatal MI risk was elevated among users of anti-platelet medication and beta-receptor blockers, respectively, but not among non-users, with […]
The American Heart Association has updated a construct of cardiovascular health (CVH), Life’s Essential 8, including diet, physical activity, nicotine exposure, sleep health, body mass index, blood lipids, blood glucose, and blood pressure. Each metric has a new scoring algorithm ranging from 0 to 100 points, allowing generation of a […]