Cardiovascular Diseases


High-Sensitivity Cardiac Troponin Prognostic in Chronic CAD

A UK prospective cohort study in patients with symptoms suggestive of stable angina suggested that cardiac troponin predicts risk of myocardial infarction or cardiovascular death independent of cardiovascular risk factors and disease severity. The study included 4,240 patients (mean age 66 years, 33% female), coronary artery disease (CAD) was identified […]


Subclinical AF Common in HF Patients

A cohort study revealed that subclinical atrial fibrillation (AF) was common in heart failure (HF) patients with preserved ejection fraction (HFpEF) and mildly reduced ejection fraction (HFmrEF). The study included 367 patients with cardiac monitoring data at baseline and follow-up in a randomized clinical trial of atrial shunt therapy. The […]


2023 Guideline for Chronic Coronary Disease

The updated American guideline provides an evidence-based and patient-centered approach to management of patients with chronic coronary disease (CCD). The guideline is based on a comprehensive literature search from September 2021 to May 2022 and includes the following top take-home messages: Emphasis is on team-based, patient-centered care. Nonpharmacological therapies, including […]


Any Exercise Counts Against CVD

The analysis of a UK cohort study suggests that a weekend warrior pattern of physical activity was associated with similarly lower risks of cardiovascular diseases (CVD) to regular activity. A total of 89 573 individuals (mean age, 62 years; 56% women) who underwent accelerometry were included. When stratified at the threshold […]


Healthy Diet Score, CVD and Mortality in World Regions

An analysis of data from international studies indicated that diets comprised of higher amounts of fruits, vegetables, nuts, legumes, and a moderate amount of fish and whole-fat dairy is associated with a lower risk of cardiovascular disease (CVD) and mortality in all world regions, especially in countries with lower income […]


Clinical Significance of LVEF Thresholds

An analysis of individual-level information of heart failure (HF) patients revealed that there was a left ventricular ejection fraction (LVEF) threshold of around 40% to 50% where the pattern of patient characteristics changed, and event rates began to increase compared with higher LVEF values. The analysis was performed on 33 699 […]


Plant-Based Diets Linked to Lower Cholesterol, LDL-C, and Apo B

A systematic review and meta-analysis revealed that vegetarian and vegan diets were consistently associated with reduced concentrations of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and apolipoprotein B (Apo B). The study included 30 randomized controlled trials published between 1980 and October 2022. Compared with omnivorous diets, the plant-based diets reduced […]


SBP <130 mmHg Beneficial for Young-Older Patients

The secondary analysis of a multicenter, randomized, controlled trial in China suggested that maintaining systolic blood pressure (SBP) at <130 mmHg offers additional cardiovascular benefits among young-older patients with high blood pressure. The trial enrolled 8511 young-older (60–80 years) hypertensive patients without prior stroke to compare the intensive treatment (SBP […]


Ambulatory BP More Informative for Mortality

A Spanish observational cohort study indicated that ambulatory blood pressure (BP), particularly night-time BP, was more informative about the risk of all-cause and cardiovascular death than clinic BP. The study used clinic and ambulatory BP data obtained from 59124 patients between March 1, 2004, to Dec 31, 2014. During a […]


Napping Duration Relevant in Health

A Spain cohort study suggested that siesta duration is relevant in obesity/metabolic syndrome (MetS). Timing of nighttime sleep and eating, energy intake at lunch, cigarette smoking, and siesta location may be potential lifestyle mediators. The study included 3275 individuals (mean age 41 years, 78% women, and average BMI 31.1) with […]