A UK longitudinal associations study revealed that hyperlipidemias and inflammation independently and together raise the risk of serious cardiovascular diseases (CVD). The risk is more closely tied to the actual blood levels of these markers than to the use or not of cholesterol-lowering medication. Data were from 322,922 participants (55.9% […]
Two recent studies highlight the importance of physical activity volume and intensity in reducing cardiovascular disease (CVD) risk and improving longevity. The first study analyzed data from over 24,000 middle-aged and older non-exercisers in the UK Biobank, examining the effects of incidental physical activity (IPA)—unstructured daily movement outside formal exercise—on […]
A prospective UK cohort study found that both self-reported average or brisk walking pace and accelerometer-measured time spent walking at moderate or brisk pace were associated with a lower risk of cardiac arrhythmias. These associations were partially mediated by metabolic and inflammatory factors. Self-reported walking pace data were available for […]
A Danish nationwide cohort study provided real world evidence that both glucagon-like peptide 1 receptor agonists (GLP1-RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT-2is) were associated with reduced rates of 3-point major adverse cardiovascular events (3P-MACE) and hospitalization for heart failure (HHF) compared to dipeptidyl peptidase 4 inhibitors (DPP-4is). Compared to […]
A US cohort study suggests that carotid artery plaque (CAP) becomes very common with increasing age among individuals without clinical atherosclerotic cardiovascular disease (ASCVD), and the association of CAP with incident ASCVD events was stronger in younger ages, especially among women. A total of 5689 participants with complete data were […]
A prospective US population-based cohort study suggested that higher intake of butter was associated with increased mortality, while higher intake of plant-based oils was associated with lower mortality. Substituting butter with plant-based oils may prevent premature deaths. There were 221 054 adults with mean age at baseline of 36.1 ~ 56.3 […]
A prespecified subgroup analysis of a Chinese randomized clinical trial suggested that salt substitution significantly reduced the risks of stroke recurrence and death. The analysis included 15 249 patients with stroke (mean age, 64.1 years; female 45.9%; male 54.1%) from an open-label, cluster randomized clinical trial. Patients were assigned to […]
A US prospective cohort analysis suggested that supine high blood pressure (BP) regardless of seated high BP was associated with a higher risk of CVD and mortality than seated high BP alone. The analysis used data from 11 369 participants without known CVD (female 55.7%, male 44.3%; Black 25.1%, White 74.9%; […]
A Spanish secondary prevention study suggested that Mediterranean diet might reduce neutrophil levels and slow the progression of atherosclerosis and was superior to a low-fat diet in preventing major events of coronary heart disease (CHD). A total of 1002 CHD patients were randomly assigned to follow either a low-fat diet […]
Top 10 key takeaway points of the report of the American College of Cardiology Solution Set Oversight Committee for the diagnosis and management of myocarditis: 1. Be aware of the 3 classic presentations of myocarditis: chest pain, heart failure/shock, and/or symptoms related to arrhythmia (eg, presyncope or syncope), especially in […]