T2D

Intensive BP Control Benefits T2D Patients

This entry was posted in Cardiovascular Diseases and tagged Intensive Blood Pressure Control Outcomes T2D on by

A Chinese parallel design, randomized clinical trial showed that the incidence of major cardiovascular events among patients with type 2 diabetes (T2D) was significantly lower with intensive treatment targeting a systolic blood pressure (SBP) of less than 120 mm Hg than with standard treatment targeting a SBP of less than […]

Early-Life Sugar Restriction Protective on T2D and High Blood Pressure

This entry was posted in Cardiovascular Diseases Uncategorized and tagged Early Life Sugar Restriction High Blood Pressure T2D on by

A study comparing UK adults conceived just before or after sugar rationing ended found that early-life sugar rationing reduced risk of type 2 diabetes (T2D) and high blood pressure (HBP). The sugar rationing ended in September 1953 restricted sugar intake to levels within current dietary guidelines, but consumption nearly doubled […]

Lipidome Changes Informative of Dietary Fat Quality and Cardiometabolic Risk

This entry was posted in Cardiovascular Diseases Health and tagged CVD Diet Lipidome Risks T2D on by

A multilipid score (MLS), reflecting the effects of replacing saturated fat with unsaturated fat on 45 lipid metabolite concentrations, was associated with significantly lower risk of cardiovascular diseases (CVD) and type 2 diabetes (T2D). The MLS was based on lipidomics data from a randomized controlled dietary intervention trial, replacing specific […]

A 5:2 Intermittent Fasting Meal Replacement Diet Beats Metformin and Empagliflozin in T2D

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A randomized, open-label, active parallel-controlled clinical trial showed that 2 nonconsecutive fasting days (with a daily energy intake of 500 kcal for women and 600 kcal for men) and 5 days of habitual intake per week and meal replacement diet (5:2 MR) achieved better glycemic control compared with metformin and […]

Prevailing Perspective of Processed/Red Meat and CAD/T2D Challenged

This entry was posted in Cardiovascular Diseases Health and tagged Genetics Meat Intake T2D on by

A Mendelian randomization (MR) analysis did not find sufficient evidence to support a causal relationship between red/processed meat consumption and cardiovascular disease (CAD), hypertension, stroke, and type 2 diabetes (T2D). The analysis used data of publicly published genome-wide association studies. The inverse-variance weighted analyses revealed no causal association between the […]

Lactase Genotype Dependent Association of Milk Intake and T2D

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An ongoing US prospective cohort study suggests that lactase (LCT) genotype may modify the relationship between milk intake and risk of type 2 diabetes (T2D), with higher milk intake associated with lower risk of T2D only in lactase non-persistent (LNP) individuals but not in lactase persistence (LP) individuals. The study […]

Time-Restricted Eating Effective for Weight Loss in T2D

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A US randomized clinical trial found that time-restricted eating (TRE) without calorie counting was effective for weight loss and lowering of HbA1c levels in T2D adults. Between January 25, 2022, and April 1, 2023, 75 adults (mean age of 55, 71% women) with T2D were randomized to 1 of 3 […]