Among US Medicare beneficiaries, colder ambient temperatures were associated with increased heart failure hospitalizations while warmer temperatures were not, and the U-shaped temperature–cardiovascular risk association seen for cardiovascular mortality did not apply to heart failure hospitalizations, according to a time-stratified case-crossover study of 1,517,756 hospitalizations from 996,312 patients (mean age, […]
Higher blood levels of the gut microbiome-derived metabolite trimethylamine N-oxide (TMAO) were independently associated with an increased risk of developing abdominal aortic aneurysms (AAAs) and experiencing serious AAA-related events in apparently healthy older adults. Researchers measured plasma TMAO levels in 4,442 community-dwelling adults aged 65 years or older from the […]
Older adults with higher cumulative daily cortisol levels experienced faster cognitive decline, while healthier day-to-day cortisol variability was linked to slower decline, suggesting that salivary cortisol may serve as an early biomarker of cognitive aging, although it was not associated with short-term Alzheimer’s disease (AD) risk. In this US prospective […]
An international analysis of nearly 1 million adults found that the long-standing differences in blood pressure and non-HDL cholesterol between older adults with obesity and those of normal weight have narrowed substantially over the past three decades, largely alongside increased use of antihypertensive and cholesterol-lowering medications. Researchers analyzed data from […]
In older adults, longer and more frequent daytime naps, particularly those occurring in the morning, were associated with a higher risk of all-cause mortality based on objective actigraphy measurements. In this prospective cohort study from the US Rush Memory and Aging Project, 1,338 community-dwelling adults (mean age 81.4 years, 76% […]