DOAC

DOACs Reduce Cardiovascular Events in Atrial Fibrillation at Intermediate Stroke Risk

This entry was posted in Cardiovascular Diseases and tagged Atrial Fibrillation DOAC Efficacy Intermediate Stroke Risk Safety on

In patients with atrial fibrillation at intermediate risk for stroke, direct oral anticoagulant (DOAC) therapy significantly reduced the 24-month risk of a composite of stroke, systemic embolism, major bleeding, or cardiovascular death compared with no anticoagulation. In the Korean multicenter, open-label, adjudicator-masked randomized trial, 1,803 patients with a CHA₂DS₂-VASc score […]

Early DOACs Post Ischemic Stroke and Atrial Fibrillation Beneficial

This entry was posted in Cardiovascular Diseases and tagged Atrial Fibrillation DOAC Stroke on

A systematic review and prospective individual participant data meta-analysis of randomized controlled trials supports early direct oral anticoagulants (DOACs) initiation within 4 days for patients with acute ischemic stroke and atrial fibrillation to reduce the risk of recurrent stroke without increasing bleeding risk. The analysis included four trials met inclusion […]