Discontinuation

Stopping Statins Noninferior to Continuing Them in Older Adults without Known CVD

This entry was posted in Cardiovascular Diseases and tagged CVD Discontinuation Old Adults Primary Prevention Statins on

Among older adults with at least two chronic conditions but no known cardiovascular disease, discontinuing statin therapy was noninferior to continuing it with respect to major cardiovascular events or death from any cause at 2 years. In this international, open-label, randomized, controlled trial, 1,880 adults aged 70 years or older […]

Stopping Statins for Primary Prevention After Age 75? Evidence from a Randomized Trial

This entry was posted in Cardiovascular Diseases and tagged Discontinuation Old Adults Primary Prevention Safety Statins on

In adults aged 75 years or older without a history of atherosclerotic cardiovascular disease (ASCVD) who were taking statins for primary prevention, discontinuing statin therapy was non-inferior to continuing treatment with respect to 3-year all-cause mortality. In the French multicentre, open-label, phase 3 randomised controlled trial, 1,180 participants were assigned […]