CVD


Adherence to Healthy Eating Matters

A US study of 3 prospective cohorts suggests that greater adherence to various healthy eating patterns was consistently associated with lower risk of cardiovascular disease (CVD). The final study sample included 74 930 women in the 1st cohort (mean baseline age, 50.2 years), 90 864 women in the 2nd cohort (mean baseline […]


CVD Risk Increased with Normal Range SBP

A US cohort study revealed that beginning with a systolic blood pressure (SBP) level of 90 mm Hg, there was a stepwise increase in the prevalence of traditional atherosclerotic cardiovascular disease (ASCVD) risk factors, coronary artery calcium, and the risk of ASCVD. The study included 1457 participants free of ASCVD […]


NOACs Safer in AF with Prior ICH

A cohort study in Taiwan suggested that among patients with atrial fibrillation (AF) with prior ICH, non–vitamin K antagonist oral anticoagulants (NOACs) use was associated with lower rates of intracranial hemorrhage (ICH) and major bleeding compared with warfarin use, whereas the rate of ischemic stroke was similar. The study included […]


Benign Prognosis of Asymptomatic Intracranial Stenosis

A prospective cohort study in England found that the prevalence ofasymptomatic intracranial stenosis (ICS) increased with age in patients with transient ischemic attack (TIA) and minor stroke, but did not increase the short- or medium-term risk of distal recurrent ischemic stroke in patients receiving standard medical treatment. The study included […]


Myocardial Injury Common and Risky in COVID-19

A retrospective cohort study in the US suggested that myocardial injury was prevalent among patients hospitalized with COVID-19, and was associated with higher risk of mortality. The study included 2736 patients (median age 66.4 years, 59.6% men) with COVID-19 admitted between February 27th and April 12th, 2020 with troponin-I (normal […]


Metoprolol and Aspirin Effective in Grief

A randomized controlled trial in Australia suggested that a low dose metoprolol and aspirin for 6 weeks reduces physiological and psychological surrogate measures of cardiovascular risk in early bereavement. After assessment within 2 weeks of bereavement, spouses (n = 73) or parents (n = 12) of deceased (aged 66.1 ± 9.4 years, 55 females) were randomized […]


Processed Meat and Red Meat Linked with CVD and Mortality

A cohort study suggests that higher intake of processed meat, unprocessed red meat, or poultry, was significantly associated with an increased risk of incident cardiovascular disease (CVD), whereas higher intake of processed meat or unprocessed red meat, was significantly associated with an increased risk of all-cause mortality. The study analyzed […]


Sex Differences in BP

Sex-specific analyses of longitudinal BP measures in US cohort studies indicate that blood pressure (BP) measures progress more rapidly in women than in men, beginning early in life. The analyses included 32 833 participants (54% female) spanning ages 5 to 98 years from 1971 to 2014 in 4 community-based US cohort […]


Common Drugs Linked to Reduced Cardiotoxicity

A meta-analysis suggested that use of beta-blockers, angiotensin converting enzyme (ACE) inhibitors, or angiotensin II receptor blockers (ARBs) in patients receiving cancer treatment linked to less heart damage. For every ten patients treated with the drugs, one case of cardiotoxicity could be avoided. The meta-analysis included 9 randomized controlled trials […]


Potential Benefit of Early Lipid-Lowering

A multinational risk-evaluation and risk-modelling study suggests that non-HDL cholesterol concentrations in blood are strongly associated with long-term risk of atherosclerotic cardiovascular disease (CVD), and highlights the potential benefit of early lipid-lowering strategies. The study identified 398 846 individuals in 38 cohorts (48·7% women; median age 51·0 years, without prevalent CVD […]