A Korean population-based cohort study suggests that intensive blood pressure (BP) control is appropriate for reducing all-cause mortality in addition to cardiorenal risk in higher- rather than lower-risk patients. A total of 1 402 975 adults aged 40 to 79 years who had no known cardiorenal disease were included from 2002 to […]
A prospective population-based cohort study in the Netherlands suggests that in individuals at low and intermediate genetic risk, favorable modifiable-risk profiles are associated with a lower risk of dementia compared to unfavorable profiles. However, these protective associations were not found in those at high genetic risk. The study included 6,352 […]
A study showed independent associations between short-term exposure to PM10 and PM2.5 and daily all-cause, cardiovascular, and respiratory mortality in more than 600 cities across the globe.Daily data on mortality and air pollution were collected from 652 cities in 24 countries or regions to evaluate the associations of inhalable particulate […]
Do MI Women Commonly Present with Atypical Symptoms? Not really, according to a prospective study in Scotland. The study included 1941 patients (39% women) with suspected acute coronary syndrome. Standardized criteria defined typical and atypical presentations based on pain nature, location, radiation, and additional symptoms. Diagnosis of myocardial infarction (MI) […]
A UK epidemiological study revealed that high and increasing blood pressure (BP) from early adulthood into midlife seems to be associated with increased white matter hyperintensity volume (WMHV) and smaller brain volumes at 69–71 years of age. The study included 502 individuals from a cohort born throughout mainland Britain in […]
A science advisory from the American Heart Association recommended that prescription n-3 fatty acids (eicosapentaenoic acid [EPA]+docosahexaenoic acid [DHA] or EPA-only) at a dose of 4 g/d (>3 g/d total EPA+DHA) are an effective and safe option for reducing triglycerides as monotherapy or as an adjunct to other lipid-lowering agents […]
A nationwide Swedish prospective propensity score–matched cohort study suggests that lipophilic statins were associated with significantly reduced hepatocellular carcinoma (HCC) incidence and mortality. The study included 16 668 adults (8334 who initiated statin use [6554 lipophilic and 1780 hydrophilic] and 8334 nonusers) among 63 279 eligible adults with chronic hepatitis B or […]
Two US studies showed that more intensive blood pressure (BP) management was associated with less progression of cerebral small vessel ischemic diseaseand a greater decrease in total brain volume; BP patterns in midlife and late life may be associated with differing risks for incident dementia. The substudy of a randomized […]
A US prospective cohort study found that while eating more red meat is associated with a greater risk of developing invasive breast cancer, eating more poultry is linked to a lower risk. The study enrolled 42,012 participants from 2003 to 2009 with a mean follow up of 7.6 years. A […]
A longitudinal population-based cohort study showed that higher 24-hour and nighttime blood pressure (BP) measurements were significantly associated with greater risks of death and a composite cardiovascular (CV) outcome. The study included 11 135 adults from Europe, Asia, and South America (median age, 54.7 years, 49.3% women) with baseline observations collected […]