A retrospective cohort study in the US suggested that myocardial injury was prevalent among patients hospitalized with COVID-19, and was associated with higher risk of mortality. The study included 2736 patients (median age 66.4 years, 59.6% men) with COVID-19 admitted between February 27th and April 12th, 2020 with troponin-I (normal […]
International cohort studies suggest that adding azithromycin to hydroxychloroquine (HCQ) treatment may increase heart failure and cardiovascular mortality, potentially due to synergistic effects on QT length of ECG. Severe adverse events associated with HCQ-azithromycin were compared to HCQ-amoxicillin in rheumatoid arthritis patients aged 18+ and followed up over 30 days. […]
A nationwide Swedish cohort study suggests that in patients with chronic viral hepatitis, low-dose (75 mg or 160 mg) aspirin use was associated with a duration-dependent significantly lower risk of incident hepatocellular carcinoma and liver-related death than no use of aspirin, without a significantly higher risk of gastrointestinal bleeding. The […]
A study in Europe supports the feasibility of improving the habitual diet to modulate the gut microbiota and potentially to promote healthier ageing. The gut microbiota were profiled in 612 non-frail or pre-frail elderly subjects across five European countries before and after the administration of a 12-month Mediterranean diet intervention. […]
A cohort study suggests that higher intake of processed meat, unprocessed red meat, or poultry, was significantly associated with an increased risk of incident cardiovascular disease (CVD), whereas higher intake of processed meat or unprocessed red meat, was significantly associated with an increased risk of all-cause mortality. The study analyzed […]
A US prospective cohort study suggested that unhealthy low-carbohydrate-diet and low-fat-diet scores were associated with higher total mortality, whereas healthy low-carbohydrate-diet and low-fat-diet scores were associated with lower total mortality. The study included 37 233 adults 20 years or older (mean age 49.7; 52.6% female) with 24-hour dietary recall data […]
A Canadian cohort study revealed that overweight and obese significantly influences blood levels of common laboratory markers, most notably liver enzymes, lipids/lipoproteins, inflammatory markers and uric acid, in children and adolescents. The study included 1,332 healthy subjects ages 5.1-19.0 years with body mass index (BMI) ranging from 13.4-65.0 kg/m2. Levels […]
A meta-analysis suggested that use of beta-blockers, angiotensin converting enzyme (ACE) inhibitors, or angiotensin II receptor blockers (ARBs) in patients receiving cancer treatment linked to less heart damage. For every ten patients treated with the drugs, one case of cardiotoxicity could be avoided. The meta-analysis included 9 randomized controlled trials […]
Dr. Bermanand Dr. Boguskisummarized the risk factors for falls in the elderly and traumatic brain injury (TBI). Risk factors for falls include lower body weakness; past history of a fall; difficulties with walking and balance; use of medicines, such as tranquilizers, sedatives, or antidepressants and medicines affect balance; vision problems; […]
A population-based cohort study in New Zealand suggested that gait speed at midlife may be a summary index of aging and brain health. The study included a representative 1972 to 1973 birth cohort of 1037 original participants (91% of eligible births; 51.6% male) and observed to age 45 years (until […]