A nationwide Swedish cohort study suggests that in patients with chronic viral hepatitis, low-dose (75 mg or 160 mg) aspirin use was associated with a duration-dependent significantly lower risk of incident hepatocellular carcinoma and liver-related death than no use of aspirin, without a significantly higher risk of gastrointestinal bleeding. The […]
A study in Europe supports the feasibility of improving the habitual diet to modulate the gut microbiota and potentially to promote healthier ageing. The gut microbiota were profiled in 612 non-frail or pre-frail elderly subjects across five European countries before and after the administration of a 12-month Mediterranean diet intervention. […]
A cohort study suggests that higher intake of processed meat, unprocessed red meat, or poultry, was significantly associated with an increased risk of incident cardiovascular disease (CVD), whereas higher intake of processed meat or unprocessed red meat, was significantly associated with an increased risk of all-cause mortality. The study analyzed […]
A US prospective cohort study suggested that unhealthy low-carbohydrate-diet and low-fat-diet scores were associated with higher total mortality, whereas healthy low-carbohydrate-diet and low-fat-diet scores were associated with lower total mortality. The study included 37 233 adults 20 years or older (mean age 49.7; 52.6% female) with 24-hour dietary recall data […]
A Canadian cohort study revealed that overweight and obese significantly influences blood levels of common laboratory markers, most notably liver enzymes, lipids/lipoproteins, inflammatory markers and uric acid, in children and adolescents. The study included 1,332 healthy subjects ages 5.1-19.0 years with body mass index (BMI) ranging from 13.4-65.0 kg/m2. Levels […]
A meta-analysis suggested that use of beta-blockers, angiotensin converting enzyme (ACE) inhibitors, or angiotensin II receptor blockers (ARBs) in patients receiving cancer treatment linked to less heart damage. For every ten patients treated with the drugs, one case of cardiotoxicity could be avoided. The meta-analysis included 9 randomized controlled trials […]
Dr. Bermanand Dr. Boguskisummarized the risk factors for falls in the elderly and traumatic brain injury (TBI). Risk factors for falls include lower body weakness; past history of a fall; difficulties with walking and balance; use of medicines, such as tranquilizers, sedatives, or antidepressants and medicines affect balance; vision problems; […]
A population-based cohort study in New Zealand suggested that gait speed at midlife may be a summary index of aging and brain health. The study included a representative 1972 to 1973 birth cohort of 1037 original participants (91% of eligible births; 51.6% male) and observed to age 45 years (until […]
A French open-label, randomized, controlled trial showed that among patients with coma who had been resuscitated from cardiac arrest with nonshockable rhythm (asystole or pulseless electrical activity), the use of moderate therapeutic hypothermia at 33°C led to a higher percentage of patients who survived with a favorable neurologic outcome at […]
A nationwide Swedish prospective propensity score–matched cohort study suggests that lipophilic statins were associated with significantly reduced hepatocellular carcinoma (HCC) incidence and mortality. The study included 16 668 adults (8334 who initiated statin use [6554 lipophilic and 1780 hydrophilic] and 8334 nonusers) among 63 279 eligible adults with chronic hepatitis B or […]