A comprehensive analysis of global burden of diseases, injuries, and risk factors concluded that alcohol use is a leading risk factor for disease burden worldwide, contributes to health loss from many causes and exacts its toll across the lifespan, and the safest level of drinking is none. The analysis used […]
A prospective US cohort study and meta-analysis suggested that both high and low percentages of carbohydrate diets were associated with increased mortality, with minimal risk observed at 50–55% carbohydrate intake. The association was modified by the source of food, with higher mortality when carbohydrates were exchanged for animal-derived fat or […]
Canadian professional groups recommended deprescribing proton pump inhibitors (PPIs) in adults who have completed a minimum of 4 weeks of PPI treatment for heartburn or mild to moderate gastroesophageal reflux disease or esophagitis, and whose symptoms are resolved. Deprescirbing by decreasing the daily dose or stopping and changing to on-demand […]
A French prospective population-based cohort study suggests that healthy diet by following dietary recommendations could significantly contribute to cancer prevention. The study investigated the associations between several nutritional scores and overall, breast, prostate, and colorectal cancer risk in a large prospective population-based cohort. The study included 41,543 participants aged ≥40 […]
A randomized noninferiority trial in Australia suggested that intermittent energy restriction is an effective alternative diet strategy for the reduction of hemoglobin A1c (HbA1c) level comparable to continuous energy restriction in patients with type 2 diabetes (T2D), and it may be superior to continuous energy restriction for weight loss. The […]
A prospective cohort study in the US revealed that adherence to a healthy lifestyle is associated with a substantially lower risk of cardiovascular disease (CVD) incidence and mortality among adults with type 2 diabetes (T2D). The study included 11,527 participants (8,970 women) with T2D diagnosed during follow-up of an average […]
A systematic review found that exercising for at least 52 hours (averaging about an hour, 3 times a week) is associated with improved cognitive performance in older adults with and without cognitive impairment. Another population-based study in Chinese suggested that active participation in intellectual activities might help prevent dementia in […]
A Dutch population-based study revealed that a better diet quality is associated with larger brain tissue volumes. The study included 4,447 participants (average age 65.7; female 56.8%) underwent dietary assessment and brain MRI scanning between 2005 and 2015, excluding participants with an implausible energy intake, prevalent dementia, or cortical infarcts. […]
A study in US adults concluded that a healthy lifestyle could substantially reduce premature mortality and prolong life expectancy. The study included 123,329 adults and defined 5 low-risk lifestyle factors as never smoking, body mass index of 18.5 to 24.9 kg/m2, ≥30 min/d of moderate to vigorous physical activity, moderate […]
The US Preventive Services Task Force has updated recommendations of exercise, but not vitamin D for fall prevention interventions in community-dwelling older adults. According to a systematically review of 62 randomized clinical trials (N = 35 058), multifactorial intervention trials were associated with a reduction in falls (incidence rate ratio [IRR], 0.79). Exercise […]