A UK prospective cohort study suggested that decaffeinated, ground, and instant coffee, particularly at 2–3 cups/day, were consistently associated with significant reductions in incident cardiovascular disease (CVD, such as coronary heart disease, heart failure, and ischemic stroke, etc.) and mortality. Ground and instant but not decaffeinated coffee was also associated with […]
A prospective study indicates that the higher frequency of adding salt to foods is associated with a higher risk of all-cause premature mortality and lower life expectancy. The study included 501 379 participants from UK biobank. There were graded relationships between higher frequency of adding salt to foods and higher concentrations […]
A prospective, multicenter biobank cohort study in the UK and US revealed that very high high-density lipoprotein cholesterol (HDL-C) levels were associated with higher mortality risk in patients with coronary artery disease (CAD). There were 14 478 UK participants (from 2006; mean age 62.1 years, 76.2% men) and 5467 US participants […]
A systematic review and meta-analysis suggests that the absolute benefits of statins are modest and may not be strongly mediated through the degree of low-density lipoprotein cholesterol (LDL-C) reduction. The analysis included 21 randomized clinical trials that examined the effectiveness of statins in reducing total mortality and cardiovascular outcomes with […]
Observational data from 2 prospective cohorts of U.S. men and women suggested that higher olive oil intake or replacing margarine, butter, mayonnaise, and dairy fat with olive oil were associated with lower risk of total and cause-specific mortality. The analysis included 60,582 women and 31,801 men from 1990 to 2018 […]
A retrospective cohort study concluded that high-grade exercise-induced premature ventricular contractions (PVCs) occurring during recovery were associated with long-term risk of cardiovascular mortality in asymptomatic individuals, but not PVCs occurring only during exercise. The study included a total of 5,486 asymptomatic individuals with a mean age of 45.4 years and […]
A German longitudinal study suggested that the association between systolic blood pressure (SBP) and all-cause mortality in older adults may be modified by frailty, with a tendency toward lower risk among those with SBP≥130 mm Hg in frail older adults. The study included 1170 participants (median age 73.9 years, 41.6% […]
A study in a large, geographically diverse population confirmed that diets with a high glycemic index were associated with an increased risk of cardiovascular disease (CVD) and death. The study included 137,851 participants between the ages of 35 and 70 years living on five continents, with 8780 deaths and 8252 […]
A systematic review and meta-analysis suggests that angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) may be associated with protective effects for patients with COVID-19. The analysis included 52 studies that evaluated clinical outcomes among 101 949 total patients, of whom 26.0% were receiving ACEIs or ARBs. When adjusted for […]
A pooled analysis of individual participant data of 4 international cohort studies suggested that fish intake of 2 servings weekly is associated with lower risk of major cardiovascular disease (CVD) and mortality among patients with prior CVD. The analysis involved 191 558 participants with a mean age of 54.1 years, 47.9% […]