Combination

Triple Low-Dose BP-Lowering Pill Reduces Recurrent Stroke After Intracerebral Hemorrhage

This entry was posted in Cardiovascular Diseases and tagged Combination High Blood Pressure Intracerebral Hemorrhage Stroke Treatment on

In patients with prior intracerebral hemorrhage, adding a single pill combining three low-dose antihypertensive agents to standard care significantly reduced recurrent stroke and major cardiovascular events compared with placebo. In this multinational, double-blind, randomized controlled trial of 1,670 clinically stable patients with baseline systolic blood pressure (BP) of 130–160 mm […]

Concomitant SSRIs and OACs Use Linked to Higher Bleeding Risk

This entry was posted in Cardiovascular Diseases Mental Disorders and tagged Bleeding Combination Oral Anticoagulants SSRIs on

A UK nested case-control study suggested that concomitant use of selective serotonin reuptake inhibitors (SSRIs) and oral anticoagulants (OACs) was associated with bleeding risk and should be closely monitored, particularly within the initial months of treatment. Between January 1998, and March 2021, 42 190 atrial fibrillation (AF) patients with major bleeding […]