Late Endovascular Thrombectomy Effective in Vertebrobasilar Artery Occlusion

A multicenter, prospective Chinese cohort study suggested that endovascular thrombectomy (EVT) plus best medical treatment (BMT) improved functional outcomes and survival in patients with vertebrobasilar artery occlusion treated beyond 24 hours after last known well time. Conducted between 2019 and 2024 across 11 comprehensive stroke centers in China, the study […]


Morning Naps Linked to Dementia Risk

A US clinical-pathologic cohort study found that more frequent morning naps were linked to a higher risk of developing Alzheimer’s dementia. Additionally, more naps in the early afternoon and more consistent nap patterns were linked to lower levels of Alzheimer’s pathology. The study analyzed data from 936 older adults (aged […]


Healthy Lifestyle’s Benefits Go beyond Weight Loss

A pooled analysis of lifestyle intervention trials suggested that adopting a healthy lifestyle can confer metabolic benefits beyond weight loss (WL) alone. The study investigated how individual responses to long-term lifestyle interventions for WL affect cardiometabolic risk by pooling data from three long-term lifestyle WL-intervention trials with adherence rates of […]


Low Sodium DASH Diet Reduced BP

A US randomized, 4-period crossover feeding study revealed that sodium reduction, especially when combined with a Dietary Approaches to Stop Hypertension (DASH)-style diet optimized for diabetes (DASH4D), can significantly lower blood pressure (BP) in patients with type 2 diabetes (T2D) and high BP, even among those already using multiple antihypertensive […]


Global Study of Stroke Risk Factors

A study revealed that stroke remains a major global health challenge, influenced by numerous risk factors that vary across regions and populations. The study analyzed stroke-related mortality from 1990 to 2021 using Global Burden of Disease 2021 data, focusing on three primary stroke subtypes: ischemic stroke, intracerebral hemorrhage, and subarachnoid […]


Antidepressants Effective and Safe in Older Adults with Anxiety

A systematic review and meta-analysis evaluated randomized controlled trials on pharmacological treatments for anxiety in adults aged 60 and older, identifying 19 eligible studies with 2,336 participants (68% women). The primary outcomes included reductions in anxiety symptoms, treatment response, or remission. Antidepressants were found to be more effective than placebo […]


Geographical Variation in Lipoprotein (a) Levels Among CHD Patients

A global study suggested that most patients with coronary heart disease (CHD) have Lipoprotein (a) [Lp(a)] levels below risk-enhancing thresholds with wide geographical variations. The study assessed Lp(a) levels in 3,928 CHD patients across 13 countries in six World Health Organization regions. Median Lp(a) level was 32 nmol/L, with 17.6% […]


The Science and Skepticism around Seed Oils

A recent article explored the science and skepticism surrounding seed oils. These oils—extracted from sources such as soy, canola, sunflower, and corn—are rich in unsaturated fats, particularly polyunsaturated fats (PUFAs) like omega-6 linoleic acid. A substantial body of evidence supports the health benefits of replacing saturated fats with PUFAs. However, […]


Bedtime Antihypertensive Comparable to Morning Use

A Canadian study of adults with high blood pressure (BP) found no difference in health outcomes between taking BP medications in the morning versus at bedtime. A total of 3,357 adult patients with high BP (56.4% female; median age, 67 years; 53.7% on monotherapy) were randomly assigned to take their […]


Obicetrapib Effective and Safe in Improving Lipids

Two randomized, controlled trials evaluated the efficacy and safety of obicetrapib, an oral cholesteryl ester transfer protein (CETP) inhibitor, in lowering low-density lipoprotein (LDL) cholesterol in patients at high risk for atherosclerotic cardiovascular disease (ASCVD). Both trials show that obicetrapib is effective in reducing LDL cholesterol, with enhanced efficacy when […]