A US longitudinal observational cohort study suggests that APOE*2 allele and lower pulse pressure predicts resistance to amyloid-beta (Aβ) deposition in advanced aging. Of 100 participants, mean age at last cognitive evaluation was 92.0 years (range 86-100). Mean follow-up time from baseline to last measured Aβ status was 12.3 years […]
A US prospective observational cohort study revealed that higher plant protein intake was associated with reductions in risk of overall and cardiovascular disease (CVD) mortality. The study included 237 036 men (57%, median ages 62.2) and 179 068 women (median age 62.0). Based on 6 009 748 person-years of observation, 77 614 deaths (18.7%; 49 297 […]
A sequential multiple-assignment randomized trial concluded that behavioral therapy (BT) and zolpidem medication produced equivalent response and remission rates for insomnia. Adding a second treatment produced an added value for those whose insomnia failed to remit with initial therapies. The study included 211 adults (132 women; mean age, 45.6 years) […]