A prospective US cohort study showed that replacement of 30 minutes/day of sitting with light physical activity (LPA) or moderate to vigorous physical activity (MVPA) was associated with lower mortality riskamong less active adults. The study included 37,924 men and 54,617 women, of which 14,415 men and 13,358 women died […]
An analysis of pooled individual participant data collected between March 25, 1985, and August 31, 2016 revealed that higher consumption of dietary cholesterol or eggs was significantly associated with higher risk of incident cardiovascular disease (CVD) and all-cause mortality in a dose-response manner. The analysis included 29 615 participants (mean age […]
A Mendelian randomization study revealed that genetically predicted endogenous testosterone is positively linked to cardiovascular disease (CVD), including thromboembolism, heart failure (HF), and myocardial infarction (MI) in men. The study identified genetic predictors of endogenous testosterone from a genome wide association study of serum testosterone conducted in 3225 men of […]
A secondary analysis of data from a US randomized clinical trial suggests that smokers with high blood pressure (BP) may have a higher rate of cardiovascular events associated with intensive BP control. Of 9361 participants in the trial, 466 were current smokers with systolic BP > 144 mm Hg at […]
A new US National Academies report updated Dietary Reference Intakes for potassium (Adequate Intake [AI] 3400 mg for man and 2600 mg for most women per day) and sodium (AI 1500 mg/day, and Chronic Risk Reduction Intake 2300 mg/day) in healthy adults. There was insufficient evidence of risk of excess […]