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Comparative Effectiveness of Common Glucose-Lowering Medications Used with Metformin

A US multicenter, parallel-group, comparative-effectiveness clinical trial showed that when added to metformin, insulin glargine and glucagon-like peptide-1 receptor agonist…

2 years ago

Artificial Sweeteners Linked to CVD Risk

A French population based prospective cohort study suggests a potential direct association between higher artificial sweetener consumption (especially aspartame, acesulfame…

2 years ago

Most Muscle Symptoms with Statin Therapy Were Not Due to Statins

An individual participant data meta-analysis concluded that most (>90%) of all reports of muscle symptoms with statin therapy were not…

2 years ago

Statins but Not PCSK9 Inhibition Linked to Adverse Neurocognitive Effects

A drug-target Mendelian randomization (MR) analysis indicated adverse neurocognitive effects related to statins but not proprotein convertase subtilisin/kexin type 9…

2 years ago

Early Time-Restricted Eating Effective for Weight Loss

A US randomized clinical trial suggested that early time-restricted eating (eTRE) was more effective for weight loss than eating over…

2 years ago

Comparative Effects of Sleeping Pills

A systematic review and network meta-analysis provided the most comprehensive data synthesis on pharmacological treatments for adults with insomnia. The…

2 years ago

Achieving T2D Treatment Goals May Extend Life Expectancy

A US decision analytical model suggested that achieving recommended goals of glycated hemoglobin (HbA1c), systolic blood pressure (SBP), low-density lipoprotein…

3 years ago

Healthy Lifestyle Linked to Longer Life without Dementia

A US prospective cohort study showed that a healthy lifestyle was associated with a longer life expectancy, and a larger…

3 years ago

Treatment for Mild Chronic Hypertension during Pregnancy Beneficial

A US open-label, multicenter, randomized trial concluded that in pregnant women with mild chronic high blood pressure (BP), a strategy…

3 years ago

Sleep Loss Predisposes to Abdominal Visceral Obesity

A US randomized, controlled, crossover study in healthy, nonobese individuals revealed that sleep restriction combined with ad libitum food promotes…

3 years ago

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