Mental Disorders

Carotid Revascularization Does Not Improve Cognition in Asymptomatic Severe Carotid Stenosis

In patients with severe asymptomatic carotid artery stenosis, carotid revascularization—either carotid artery stenting (CAS) or carotid endarterectomy (CEA)—added to intensive…

2 weeks ago

Early Brain Ageing Linked to the Gut–Brain Axis

Higher functional-connectivity-derived brain age deviation was consistently associated with poorer cognitive performance—particularly working memory and executive function—and greater depressive symptoms…

3 weeks ago

Domain-Specific Physical Activity and Dementia Risk

Higher levels of physical activity were associated with lower risks of all-cause dementia, Alzheimer’s disease, and vascular dementia, but the…

2 months ago

Midlife Vascular Health Linked to Up to 12.6 More Dementia-Free Years

Maintaining optimal vascular health in midlife was associated with up to 12.6 additional years of life free from dementia between…

2 months ago

Limiting Sugar in the First 1,000 Days of Life May Reduce Dementia Risk Decades Later

Restricting sugar intake during the first 1,000 days from conception was associated with a lower risk of dementia, delayed disease…

2 months ago

WHO Dementia Prevention Guidelines Updated

To reduce the risk of cognitive decline and/or dementia specifically, the WHO just released updated guidance and dementia-specific recommendations: cognitive…

3 months ago

Salivary Cortisol Patterns May Indicate Cognitive Aging

Older adults with higher cumulative daily cortisol levels experienced faster cognitive decline, while healthier day-to-day cortisol variability was linked to…

3 months ago

Ketogenic Diet Beneficial in Schizophrenia and Bipolar Disorder

A randomized controlled trial found that a ketogenic diet significantly improved metabolic health, cognitive performance, and psychiatric symptoms in people…

3 months ago

Smell Loss Linked to Depression

Subjective olfactory impairment (self-reported smell loss) is consistently associated with a higher likelihood of depression, whereas objectively measured olfactory impairment…

3 months ago

Lifestyle Intervention May Slow Early Cerebral Small-Vessel Injury

A secondary MRI analysis of the US POINTER randomized clinical trial found that a structured multidomain lifestyle intervention slowed the…

3 months ago

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