The American Cancer Society (ACS) concludes that the benefits of PSA-based screening for prostate cancer outweigh the harms, recommending biennial…
Proton pump inhibitor (PPI) use was modestly associated with incident dementia in older adults (pooled HR = 1.18), but the…
Extended follow-up of three major trials consistently shows that an initial invasive strategy does not improve long-term survival or reduce…
Escitalopram, duloxetine, and agomelatine achieved higher sustained response rates than fluoxetine, while escitalopram and duloxetine also showed lower all-cause discontinuation,…
Targeting a systolic blood pressure (BP) of less than 120 mm Hg lowered the incidence of major cardiovascular events compared…
In patients with type 2 diabetes (T2D) and high cardiovascular risk, targeting a systolic blood pressure (BP) of less than…
Among older adults with at least two chronic conditions but no known cardiovascular disease, discontinuing statin therapy was noninferior to…
Two randomized, placebo-controlled trials of targeted therapies—ziltivekimab, a monoclonal antibody neutralizing interleukin-6, and pelacarsen, an antisense oligonucleotide lowering lipoprotein(a)—both failed…
Among US Medicare beneficiaries, colder ambient temperatures were associated with increased heart failure hospitalizations while warmer temperatures were not, and…
In the 10-year extended follow-up of the DECISION-CTO trial, an initial strategy of percutaneous coronary intervention (PCI) for chronic total…
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