CCTA-Guided PCI Noninferior to IVUS-Guided PCI

2 weeks ago

In a randomized, open-label, noninferiority trial, a coronary computed tomographic angiography (CCTA)–guided percutaneous coronary intervention (PCI) strategy was noninferior to…

Left Bundle-Branch Area Pacing vs Right Ventricular Pacing in Atrioventricular Block

2 weeks ago

A randomized trial found that left bundle-branch area pacing (LBBAP) significantly reduced the risk of major clinical events, particularly heart…

Familial Hypercholesterolaemia Linked to Accelerated Thymic Ageing

3 weeks ago

Familial hypercholesterolaemia (FH) is associated with reduced thymic output and accelerated thymic ageing, while statin treatment may help preserve immune…

Percutaneous Shunt Closure Improves Oxygenation in Platypnea-Orthodeoxia Syndrome

3 weeks ago

Percutaneous closure of an interatrial shunt significantly improves oxygenation and symptoms in patients with platypnea-orthodeoxia syndrome (POS), with a low…

A Female Life Stage Framework for Cardiovascular Health Across the Lifespan

3 weeks ago

A new multisociety scientific statement introduces the Female Life Stage framework to improve cardiovascular disease prevention and management in girls…

Low Protein Intake Linked to Higher Risks of Kidney Failure and Death in CKD

3 weeks ago

A prospective cohort study of 1,861 patients with nondialysis-dependent chronic kidney disease (CKD) in South Korea found that very low…

SGLT2 Inhibitors Modestly Increase Hemoglobin and Hematocrit

3 weeks ago

A meta-analysis of 85 randomized clinical trials involving 70,543 participants found that sodium-glucose cotransporter 2 (SGLT2) inhibitors were associated with…

Endovascular Therapy for Mild and Late-Presenting Acute Ischemic Stroke: Benefits and Safety

3 weeks ago

Two randomized trials conducted in China found that endovascular therapy improved functional outcomes in patients with acute ischemic stroke caused…

Circadian Depression Subtype Linked to More Severe Symptoms and Poorer Antidepressant Response

3 weeks ago

A circadian subtype of depression is associated with earlier disease onset, more severe clinical features, poorer response to commonly prescribed…

Frequent and Unintentional Daytime Napping Linked to Higher Dementia Risk

4 weeks ago

A longitudinal study of 995 U.S. older adults found that frequent and unintentional daytime napping was associated with an increased…

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