Cardiovascular Diseases

Effects of Sacubitril/Valsartan Compared With ARBs or CCBs

A meta-analysis of 15 randomized controlled trials involving 4,824 patients with high blood pressure found that sacubitril/valsartan significantly improved multiple…

2 weeks ago

Chronic Inflammation: A Common Pathway Linking Genetic and Environmental Cardiovascular Risk

Higher levels of chronic systemic inflammation were associated with smaller left ventricular volumes, compensatory increases in heart rate, and substantially…

2 weeks ago

Carotid Revascularization Does Not Improve Cognition in Asymptomatic Severe Carotid Stenosis

In patients with severe asymptomatic carotid artery stenosis, carotid revascularization—either carotid artery stenting (CAS) or carotid endarterectomy (CEA)—added to intensive…

2 weeks ago

Exercise-Based Cardiac Rehabilitation Improves Outcomes in Coronary Heart Disease

A 2026 Cochrane systematic review and meta-analysis of 107 randomized trials involving 26,886 adults with coronary heart disease (CHD) found…

2 weeks ago

Nighttime Light Exposure Linked to Higher Cardiovascular Risk

Higher nighttime light exposure was associated with adverse changes in cardiac structure and function and increased risks of cardiovascular disease…

3 weeks ago

Rising Prevalence of Unruptured Intracranial Aneurysms Over the Past Two Decades

A systematic review and meta-analysis found that the prevalence of unruptured intracranial aneurysms (UIAs) is increasing, particularly over the past…

1 month ago

Silent Atherosclerosis Common in Early Adulthood and Progressively Worsening with Age

Silent atherosclerosis was detectable as early as young adulthood and became progressively more prevalent and extensive with age, with a…

1 month ago

Function-Guided Complete Revascularization Improves Outcomes in STEMI

In patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease, complete coronary revascularization guided by functional coronary…

1 month ago

2026 Fifth Universal Definition of Myocardial Infarction

The Fifth Universal Definition of Myocardial Infarction (MI) updates the classification of MI by defining three major clinical settings—primary MI,…

1 month ago

Catheter-Directed Thrombolysis Improves Outcomes in Intermediate-High–Risk Pulmonary Embolism

In patients with intermediate-high–risk acute pulmonary embolism, catheter-directed thrombolysis with alteplase plus anticoagulation significantly reduced the 7-day risk of death,…

1 month ago

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