Cardiovascular Diseases

Atorvastatin Prevents Cardiovascular Events in Older Adults without Prior Cardiovascular Disease

In a large randomized trial, atorvastatin 40 mg daily significantly reduced major cardiovascular events by 30% among community-dwelling adults aged…

1 month ago

Aficamten Improves Exercise Capacity and Health Status in Nonobstructive HCM

In patients with symptomatic nonobstructive hypertrophic cardiomyopathy (HCM), aficamten significantly improved exercise capacity and patient-reported health status compared with placebo…

1 month ago

DOACs Reduce Cardiovascular Events in Atrial Fibrillation at Intermediate Stroke Risk

In patients with atrial fibrillation at intermediate risk for stroke, direct oral anticoagulant (DOAC) therapy significantly reduced the 24-month risk…

1 month ago

Recombinant Shingles Vaccine Linked to Reduced Cardiovascular Risk

The recombinant shingles vaccine was associated with a 9% reduction in overall cardiovascular burden over 7 years among adults aged…

1 month ago

Longitudinal Heart Stress Status Predicts CVD and Mortality in Older Adults

In community-dwelling older adults without prior cardiovascular disease (CVD), new or persistent heart stress (HS)—defined by elevated NT-proBNP concentrations over…

2 months ago

Stopping Statins for Primary Prevention After Age 75? Evidence from a Randomized Trial

In adults aged 75 years or older without a history of atherosclerotic cardiovascular disease (ASCVD) who were taking statins for…

2 months ago

Left Ventricular Size and Mortality Risk in Heart Failure

A Chinese nationwide study of 273,921 patients hospitalized with heart failure (HF) found a U-shaped association between left ventricular end-diastolic…

2 months ago

Extended-Window Thrombolysis Improves Functional Outcomes After Acute Ischemic Stroke

A systematic review and meta-analysis found that intravenous thrombolysis (IVT) given 4.5 hours or more after acute ischemic stroke onset…

2 months ago

Central Adiposity Improves Cardiovascular Risk Assessment Beyond BMI

Waist circumference (WC) and waist-to-hip ratio (WHR) identified important differences in cardiovascular disease (CVD) risk that were not captured by…

2 months ago

Midlife Vascular Health Linked to Up to 12.6 More Dementia-Free Years

Maintaining optimal vascular health in midlife was associated with up to 12.6 additional years of life free from dementia between…

2 months ago

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