Cardiovascular Diseases

Heart Failure in the United States: Rising Burden and Unmet Needs

Heart failure (HF) affects nearly 1 in 4 Americans over their lifetime, and its growing prevalence, rising mortality, widening disparities,…

1 month ago

Effects of Sacubitril/Valsartan Compared With ARBs or CCBs

A meta-analysis of 15 randomized controlled trials involving 4,824 patients with high blood pressure found that sacubitril/valsartan significantly improved multiple…

2 months ago

Chronic Inflammation: A Common Pathway Linking Genetic and Environmental Cardiovascular Risk

Higher levels of chronic systemic inflammation were associated with smaller left ventricular volumes, compensatory increases in heart rate, and substantially…

2 months ago

Carotid Revascularization Does Not Improve Cognition in Asymptomatic Severe Carotid Stenosis

In patients with severe asymptomatic carotid artery stenosis, carotid revascularization—either carotid artery stenting (CAS) or carotid endarterectomy (CEA)—added to intensive…

2 months ago

Exercise-Based Cardiac Rehabilitation Improves Outcomes in Coronary Heart Disease

A 2026 Cochrane systematic review and meta-analysis of 107 randomized trials involving 26,886 adults with coronary heart disease (CHD) found…

2 months ago

Nighttime Light Exposure Linked to Higher Cardiovascular Risk

Higher nighttime light exposure was associated with adverse changes in cardiac structure and function and increased risks of cardiovascular disease…

2 months ago

Rising Prevalence of Unruptured Intracranial Aneurysms Over the Past Two Decades

A systematic review and meta-analysis found that the prevalence of unruptured intracranial aneurysms (UIAs) is increasing, particularly over the past…

2 months ago

Silent Atherosclerosis Common in Early Adulthood and Progressively Worsening with Age

Silent atherosclerosis was detectable as early as young adulthood and became progressively more prevalent and extensive with age, with a…

2 months ago

Function-Guided Complete Revascularization Improves Outcomes in STEMI

In patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease, complete coronary revascularization guided by functional coronary…

2 months ago

2026 Fifth Universal Definition of Myocardial Infarction

The Fifth Universal Definition of Myocardial Infarction (MI) updates the classification of MI by defining three major clinical settings—primary MI,…

2 months ago

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