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Early Time-of-Day Immunotherapy Shows Survival Benefit in Lung Cancer Trial

In a Chinese phase 3 trial (LungTIME-C01) involving 210 patients with advanced non-small cell lung cancer, administering anti-PD-1 immunotherapy before…

4 months ago

Herpes Zoster Vaccine May Effectively Prevent Dementia

A large natural experiment study in Ontario, Canada, found that receiving the live attenuated herpes zoster vaccine significantly reduced the…

4 months ago

Night Shift Work Linked to Higher Cardiovascular–Kidney–Metabolic Risk, Especially With Short Sleep

Long-term and intensive night shift work was associated with a significantly higher risk of cardiovascular–kidney–metabolic (CKM) disease in a large…

5 months ago

Prediabetes Remission Confers Long-Term Protection against CVD

Achieving remission of prediabetes was associated with an approximately 50% lower long-term risk of death from cardiovascular disease (CVD) or…

5 months ago

Even Moderate Drinking Raises Cancer Risk across Multiple Cancer Types

Even moderate alcohol consumption was consistently linked to a higher risk of multiple cancers, with clear dose–response relationships showing that…

6 months ago

Corticosteroids Reduce Short-Term Deaths in Severe Pneumonia and ARDS

Adjunct low-dose, short-course corticosteroids probably reduce short-term mortality in adults with severe pneumonia or acute respiratory distress syndrome (ARDS), according…

6 months ago

Mental Wellbeing Mitigated IBS Risk

Better mental wellbeing substantially reduces the risk of developing irritable bowel syndrome (IBS), with effects that are independent of genetic…

6 months ago

Physical Activity Midlife or Late Life Linked to Lower Dementia Risk

Higher physical activity in midlife and late life—but not early adulthood—is associated with a significantly lower risk of both all-cause…

7 months ago

Clonal Hematopoiesis Linked to Heart Failure Risk

Clonal hematopoiesis of indeterminate potential (CHIP), particularly non-DNMT3A CHIP subtypes, is an independent risk factor for incident heart failure (HF)…

7 months ago

Fish-Oil Supplementation Reduced Cardiovascular Events in Patients Receiving Hemodialysis

Daily supplementation with n−3 polyunsaturated fatty acids (fish oil) significantly reduced the risk of serious cardiovascular events in patients receiving…

7 months ago

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