A 20-year follow-up study in the Netherland concluded that initiation of statin therapy during childhood in patients with familial hypercholesterolemia (FH) slowed the progression of carotid intima–media thickness and reduced the risk of cardiovascular disease in adulthood. Of the original cohort, 184 of 214 FH patients and 77 of 95 […]
A systematic review and meta-analysis suggested that global prevalence of hypertension in children is becoming more common. The analysis included 47 studies of children ages 6 to 19, from 1994 to 2018 with at least 3 separate blood pressure measurements. Standardized definitions of hypertension was based on the fourth report […]
A French open-label, randomized, controlled trial showed that among patients with coma who had been resuscitated from cardiac arrest with nonshockable rhythm (asystole or pulseless electrical activity), the use of moderate therapeutic hypothermia at 33°C led to a higher percentage of patients who survived with a favorable neurologic outcome at […]
A meta-analysis and systematic review suggested that optimism is associated with a lower risk of events of cardiovascular diseases (CVD) and all-cause mortality. The analysis included 15 studies of 229 391 participants, in which 10 studies reported data on CVD events (including CVD mortality, nonfatal myocardial infarction, stroke, and/or new-onset angina) […]
A Japanese prospective cohort study revealed that higher plant protein intake was associated with lower total and cardiovascular disease (CVD)-related mortality. The study included 70 696 participants aged 45 to 74 years (54.5% women) from January 1, 1995, through December 31, 1999, with follow-up completed December 31, 2016. Dietary intake […]
A Korean population-based cohort study suggests that intensive blood pressure (BP) control is appropriate for reducing all-cause mortality in addition to cardiorenal risk in higher- rather than lower-risk patients. A total of 1 402 975 adults aged 40 to 79 years who had no known cardiorenal disease were included from 2002 to […]
Do MI Women Commonly Present with Atypical Symptoms? Not really, according to a prospective study in Scotland. The study included 1941 patients (39% women) with suspected acute coronary syndrome. Standardized criteria defined typical and atypical presentations based on pain nature, location, radiation, and additional symptoms. Diagnosis of myocardial infarction (MI) […]
A UK epidemiological study revealed that high and increasing blood pressure (BP) from early adulthood into midlife seems to be associated with increased white matter hyperintensity volume (WMHV) and smaller brain volumes at 69–71 years of age. The study included 502 individuals from a cohort born throughout mainland Britain in […]
A science advisory from the American Heart Association recommended that prescription n-3 fatty acids (eicosapentaenoic acid [EPA]+docosahexaenoic acid [DHA] or EPA-only) at a dose of 4 g/d (>3 g/d total EPA+DHA) are an effective and safe option for reducing triglycerides as monotherapy or as an adjunct to other lipid-lowering agents […]
Two US studies showed that more intensive blood pressure (BP) management was associated with less progression of cerebral small vessel ischemic diseaseand a greater decrease in total brain volume; BP patterns in midlife and late life may be associated with differing risks for incident dementia. The substudy of a randomized […]