A randomized clinical study of specifically designed isoenergetic diets, together with fecal shotgun metagenomics, showed that a select group of short-chain fatty acid (SCFA)-producing strains of the gut microbiota was promoted by dietary fibers, and correlated with improved blood-glucose regulation in type 2 diabetes mellitus (T2D). The improvement in hemoglobin A1c levels was partly via increased glucagon-like peptide-1 production. Promotion of the positive responders diminished producers of metabolically detrimental compounds such as indole and hydrogen sulfide. SCFAs act as an energy source to the colonic epithelium and are also sensed by host signaling pathways that modulate appetite and inflammation. Deficiency of gut SCFAs is associated with T2D. The gut microbiota benefits humans via SCFA production from carbohydrate fermentation. Source: http://science.sciencemag.org/
Higher daytime light exposure was associated with a significantly lower risk of developing dementia, while…
Children and adolescents who regularly consume sugar-sweetened beverages (SSBs) and fruit juice may face a…
Women who consistently performed resistance training had a substantially lower risk of major cardiovascular disease…
US Adults with prediabetes who participated in an intensive lifestyle intervention had a significantly lower…
The impact of late-life high blood pressure (BP) on dementia risk appears to depend on…
A U.S. study found that receiving the recombinant herpes zoster vaccine (RZV, shingles vaccine) was…
This website uses cookies.