Statins

Statin Adverse Effects Analysis: Separating Signal from Noise

This entry was posted in Cardiovascular Diseases and tagged Adverse Effects Meta analysis Statins on by

To address uncertainties in statin safety profiles, which are often based on observational data susceptible to bias, researchers conducted a definitive meta-analysis of individual participant data from major double-blind, randomized controlled trials. The study first identified all undesirable effects listed in the official Summaries of Product Characteristics (SmPCs) for five […]

Statins Still Beneficial in Old and Very Old Adults

This entry was posted in Cardiovascular Diseases and tagged Old Adults Primary Prevention Statins on by

A Chinese sequential target trial emulation comparing matched cohorts initiating versus not initiating statin therapy suggested benefits and safety of statin therapy in adults aged ≥75 years, even ≥85 years. The trial included persons 75 years or older who met indications for statin initiation from January 2008 to December 2015 […]