Meta analysis

Domain-Specific Physical Activity and Dementia Risk

This entry was posted in Mental Disorders and tagged Dementia Domain Meta analysis Physical Activity on

Higher levels of physical activity were associated with lower risks of all-cause dementia, Alzheimer’s disease, and vascular dementia, but the associations differed substantially by physical activity domain. In this systematic review and meta-analysis, 74 cohort and case–control studies involving 4,227,297 participants were analyzed, with a median follow-up of 10.0 years. […]

Statin Adverse Effects Analysis: Separating Signal from Noise

This entry was posted in Cardiovascular Diseases and tagged Adverse Effects Meta analysis Statins on

To address uncertainties in statin safety profiles, which are often based on observational data susceptible to bias, researchers conducted a definitive meta-analysis of individual participant data from major double-blind, randomized controlled trials. The study first identified all undesirable effects listed in the official Summaries of Product Characteristics (SmPCs) for five […]