A US prospective observational study showed that high levels of physical activity are associated with prevalent coronary artery calcification (CAC) but are not associated with increased all-cause or cardiovascular disease (CVD) mortality after a decade of follow-up, even in the presence of clinically significant CAC levels. The study included 21 […]
An US randomized crossover study showed that chronic dietary red meat increases systemic trimethylamine N-oxide (TMAO) levels through enhanced dietary precursors, increased microbial trimethylamine (TMA)/TMAO production from carnitine, but not choline, and reduced renal TMAO excretion. Discontinuation of dietary red meat reduces plasma TMAO within 4 weeks. There were 113 healthy […]
A prospective global cohort study suggested that total sleep duration of 6–8 h per day is associated with the lowest risk of deaths and major cardiovascular events (MCEs). Daytime napping is associated with increased risks of MCEs and deaths in those with >6 h of nighttime sleep but not in those sleeping […]
A population-based, prospective cohort study in Iceland revealed that the long-term mortality risk of unrecognized myocardial infarction (UMI) can be as high as clinically recognized myocardial infarction (RMI). 935 participants (aged 67-93 years, 48.3% men) were characterized with cardiac magnetic resonance (CMR) from January 2004 to January 2007 and followed […]
Two prospective cohort studies revealed that physical activity was associated with a lower risk of mortality both in the general population and in patients with stable coronary heart disease worldwide. The 1st study included 130 843 participants without pre-existing cardiovascular disease, and followed 6·9 years. Higher physical activity was associated with […]