A comprehensive prospective study tracking over 159,000 adults for up to three decades has provided compelling evidence that multiple healthy dietary patterns protect cognitive function, with the DASH diet demonstrating the most powerful effects. Researchers simultaneously evaluated six dietary approaches—including the Mediterranean-style AHEI-2010, plant-based hPDI, environmentally-focused PHDI, and diets targeting […]
A comprehensive new Cochrane review of 22 studies involving nearly 2,000 participants over six months to one year has found that intermittent fasting may offer little to no significant benefit over standard dietary advice for weight loss in people with overweight or obesity. When compared to regular, calorie-restricted diet plans, […]
A large-scale study involving 103,649 UK Biobank participants has revealed that adhering to healthy dietary patterns is significantly associated with lower mortality rates and a longer lifespan. Over a median follow-up of 10.6 years, researchers found that five specific diets—the Alternate Healthy Eating Index-2010, Alternate Mediterranean Diet (AMED), healthful Plant-based […]
To address uncertainties in statin safety profiles, which are often based on observational data susceptible to bias, researchers conducted a definitive meta-analysis of individual participant data from major double-blind, randomized controlled trials. The study first identified all undesirable effects listed in the official Summaries of Product Characteristics (SmPCs) for five […]
In a Chinese phase 3 trial (LungTIME-C01) involving 210 patients with advanced non-small cell lung cancer, administering anti-PD-1 immunotherapy before 3:00 PM nearly doubled progression-free survival (11.3 vs. 5.7 months) and significantly improved overall survival (28.0 vs. 16.8 months) compared to later infusions. This early time-of-day treatment was linked to […]