Monthly Archives: April 2023


Napping Duration Relevant in Health

A Spain cohort study suggested that siesta duration is relevant in obesity/metabolic syndrome (MetS). Timing of nighttime sleep and eating, energy intake at lunch, cigarette smoking, and siesta location may be potential lifestyle mediators. The study included 3275 individuals (mean age 41 years, 78% women, and average BMI 31.1) with […]


Heterogeneity in BP-Lowering Effects of 4 Drugs

A Swedish randomized, double-blind, repeated crossover trial revealed substantial heterogeneity in blood pressure (BP) response to drug therapy for high BP. There were 280 participants with grade 1 high BP at low risk for cardiovascular events (54% men; mean age, 64 years). Each participant was randomized to treatment with 4 […]


Different Genetical and Environmental Contributions in Obesity to CVD

National cohort data from Swedish twins indicate that genetically related obesity is not associated with negative health outcomes to the same extent as environmentally related obesity. A total of 17,988 twins born before 1959 were enrolled in sub-studies of the Swedish Twin Registry between 1984 and 2010 and followed on […]


Family History of Heart Disease Still Matters

A cross-sectional analysis suggested that a multivariable model of clinical and genetic risk factors explains only 36% of the likelihood of family history of heart disease (FHHD), with most of the risk of a FHHD unexplained. The analysis included 166,714 UK Biobank participants with 43.2% reported a FHHD. In the […]