A UK prospective cohort study suggested that decaffeinated, ground, and instant coffee, particularly at 2–3 cups/day, were consistently associated with significant reductions in incident cardiovascular disease (CVD, such as coronary heart disease, heart failure, and ischemic stroke, etc.) and mortality. Ground and instant but not decaffeinated coffee was also associated with […]
A US multicenter, parallel-group, comparative-effectiveness clinical trial showed that when added to metformin, insulin glargine and glucagon-like peptide-1 receptor agonist liraglutide were significantly, albeit modestly, more effective in achieving and maintaining target glycated hemoglobin levels than sulfonylurea glimepiride or dipeptidyl peptidase 4 inhibitor sitagliptin in patients with type 2 diabetes […]
A double‐blind, randomized, sham‐controlled trial concluded that high‐resistance inspiratory muscle strength training (IMST) improves blood pressure (BP) and endothelial function in midlife/older adults with above‐normal initial systolic BP. Thirty‐six participants of 50–79 years old with systolic BP ≥120 mm Hg were randomized to high‐resistance IMST (75% maximal inspiratory pressure, 30 breaths/day, 6 days/week, n=18) or […]
A French population based prospective cohort study suggests a potential direct association between higher artificial sweetener consumption (especially aspartame, acesulfame potassium, and sucralose) and increased cardiovascular disease (CVD) risk. The study included 103 388 participants of the web-based cohort (mean age 42.2 years, 79.8% female, 904 206 person years) from 2009 to […]