A US cohort study suggested that in the absence of evidence of end-organ damage, conservative management of inpatient high blood pressure (BP) was associated with improved outcomes compared with more intensive management. The study included 22 834 adults hospitalized for noncardiovascular diagnoses from January 1 to December 31, 2017 (mean age, […]
A harmonized meta-analysis concluded that longer sedentary time is associated with higher mortality in less active individuals when measured by accelerometry. About 30–40min of moderate-to-vigorous-intensity physical activity (MVPA) per day attenuate the association between sedentary time and risk of death. The analysis included 44370 middle-aged and older men and women […]
Ten metabolites from seven prospective cohort studies were found to be associated with risk of stroke. The studies included 1,791 incident stroke events among 38,797 participants. Independent of traditional risk factors including hypertension, diabetes, smoking, and body mass index, amino acid histidine (hazard ratio [HR] per standard deviation [SD] = […]
Two studies suggest that low-density lipoprotein cholesterol (LDL-C) may not to be the main lipid contributor to atherosclerotic cardiovascular disease (ASCVD). The study in Spain included 6901 subjects in the high-risk primary prevention trial population (mean age: 67 years; body mass index: 30 kg/m2; 43% men; 48% with diabetes) with […]
A US randomized clinical trial revealed that a low-fat plant-based diet is effective in reducing body weight and increasing insulin sensitivity and postprandial metabolism. A total of 244 participants with body mass index of 28 to 40 (87% female, 48% White, mean age 54.4 years) were randomized in a 1:1 […]