The American Heart Association scientific statement systematically reviewed data on the potential benefits of meditation on cardiovascular risk. Neurophysiological and neuroanatomical studies demonstrate that meditation can have long‐standing effects on the brain, which provide some biological plausibility for beneficial consequences on the physiological basal state, physiological responses, and on cardiovascular […]
Two studies showed that there is no benefit of supplemental oxygen in nonhypoxic patients with suspected myocardial infarction (MI) or acute stroke. A total of 6629 patients with suspected MI and an oxygen saturation of 90% or higher were randomly assigned to receive either supplemental oxygen (6 liters per minute […]
Two prospective cohort studies revealed that physical activity was associated with a lower risk of mortality both in the general population and in patients with stable coronary heart disease worldwide. The 1st study included 130 843 participants without pre-existing cardiovascular disease, and followed 6·9 years. Higher physical activity was associated with […]
An analysis of individual level pooled data from 10 prospective cohort studies concluded that obesity is associated with earlier onset of heart failure (HF), increased risk of HF; and greater proportion of life lived with HF in the context of shorter total longevity. A total of 170,205 adults free from […]
Findings from a prospective cohort study challenge current global dietary guidelines. A total of 135 335 individuals aged 35 to 70 years without cardiovascular disease (CVD) were enrolled between Jan 1, 2003, and March 31, 2013 from 613 communities in 18 low-income, middle-income, and high-income countries in seven geographical regions globally. […]
A randomized, double-blind trial of canakinumab targeting interleukin-1β innate immunity pathway revealed a significantly lower rate of recurrent cardiovascular events in patients of myocardial infarction (MI). The trial included 10,061 patients with previous MI and a high-sensitivity C-reactive protein （hsCRP） level of 2 mg or more per liter. Canakinumab (at […]
Patient-reported outcomes among participants who received intensive BP treatment were similar to those among participants who received standard treatment. A total of 9361 participants with hypertension at high risk for cardiovascular disease were randomly assigned to a systolic blood-pressure (SBP) target of less than 120 mm Hg or 140 mm […]
A prospective cohort study of a general Japanese population demonstrated a significant independent association between increased day-to-day blood pressure variability (BPV) measured with home blood pressure monitoring and risk of dementia. The study included 1674 community-dwelling Japanese elderly without dementia, ≥60 years of age, and followed up for 5 years […]
A study revealed that estimated sodium intake (ESI) >3.7 g/day is associated with adverse cardiac remodeling and function. The study performed speckle-tracking analysis on echocardiograms with available urinary sodium data (N = 2,996). Mean age of participants was 49 ± 14 years, 57% were female, 50% were African American, and […]
A mendelian randomization study concluded that a genetic predisposition to higher serum calcium levels was associated with increased risk of coronary artery disease (CAD) and myocardial infarction (MI). The study included 60 801 CAD cases (approximately 70% with MI) and 123 504 noncases, with baseline data collected from 1948 and populations derived […]