Cardiovascular Diseases

Effect of Calcium and Vitamin D Supplements on Mortality

The post hoc analysis of postintervention follow-up of calcium and vitamin D (CaD) supplements suggested reduced cancer mortality and increased cardiovascular disease (CVD) mortality. The multicenter trial across the US included 36 282 postmenopausal women randomized 1:1 to 1000 mg of calcium carbonate (400 mg of elemental calcium) with 400 IU of vitamin D3 daily or placebo for 7 years. For women assigned to CaD vs placebo, a 7% reduction in cancer mortality was observed with a median cumulative follow-up of 22.3 years (1817 vs. 1943 deaths; hazard ratio [HR], 0.93), along with a 6% increase in CVD mortality (2621 vs. 2420 deaths; HR, 1.06). There was no effect on all-cause mortality (7834 vs. 7748 deaths; HR, 1.00). Estimates for cancer incidence varied widely when stratified by whether participants reported supplement use before randomization, whereas estimates on mortality did not vary, except for CVD mortality. The findings provide evidence of long-term effects of CaD supplementation on mortality in postmenopausal women. Source: https://www.acpjournals.org/

hyangiu

Recent Posts

Mediterranean Diet May Slow Atherosclerosis Progression and Prevent CHD

A Spanish secondary prevention study suggested that Mediterranean diet might reduce neutrophil levels and slow…

4 days ago

2024 Strategies and Criteria for the Diagnosis and Management of Myocarditis

Top 10 key takeaway points of the report of the American College of Cardiology Solution…

2 weeks ago

Irregular Sleep Linked to Higher CVD Risk

A UK device-based prospective study suggested that irregular sleep was associated with higher risk of…

4 weeks ago

Intensive BP Control Benefits T2D Patients

A Chinese parallel design, randomized clinical trial showed that the incidence of major cardiovascular events…

1 month ago

Early-Life Sugar Restriction Protective on T2D and High Blood Pressure

A study comparing UK adults conceived just before or after sugar rationing ended found that…

1 month ago

Cold Weather Linked to Higher MI Risk

A Chinese nationwide case-crossover study revealed that lower temperatures were associated with higher risks of…

2 months ago

This website uses cookies.