A meta-analyses and metaregressions concluded that the beneficial effects of salt substitutes on blood pressure and clinical outcomes were consistent and might be generalizable across diverse population subgroups worldwide. The study included 21 trials and 31 949 participants, with 19 reporting effects on blood pressure and 5 reporting effects on clinical outcomes. Overall reduction of systolic blood pressure (SBP) and diastolic blood pressure (DBP) was −4.61 and −1.61 mm Hg, respectively. Reductions in blood pressure appeared to be consistent across geographical regions and population subgroups defined by age, sex, history of hypertension, body mass index, baseline blood pressure, baseline 24-hour urinary sodium and baseline 24-hour urinary potassium. Metaregression indicated that each 10% lower proportion of sodium chloride in the salt substitute was associated with a −1.53 and −0.95 mm Hg greater reduction in SBP and DBP, respectively. There were clear protective effects of salt substitute on total mortality (risk ratio [RR] 0.89), cardiovascular mortality (RR 0.87) and cardiovascular events (RR 0.89). The findings suggest that sodium-reduced, potassium-enriched salt should be considered to reduce the burden of blood pressure-related diseases and to prevent complications in patients with hypertension. Source: https://heart.bmj.com/
Two recent studies highlight the importance of physical activity volume and intensity in reducing cardiovascular…
A prospective UK cohort study found that both self-reported average or brisk walking pace and…
A U.S. randomized clinical trial found that 4:3 intermittent fasting (IMF) led to slightly greater…
A Danish nationwide cohort study provided real world evidence that both glucagon-like peptide 1 receptor…
A systematic review and meta-analysis of placebo-controlled randomized trials showed that there is moderate certainty…
A US cohort study indicated that statin use may reduce the risks of hepatocellular carcinoma…
This website uses cookies.