A systematic review and meta-analysis suggested that untreated white coat hypertension (WCH, isolated elevated office blood pressure [BP]), but not treated white coat effect (WCE, treated WCH), is associated with an increased risk for cardiovascular events and all-cause mortality. The analysis included 27 observational studies, comprising 25 786 participants with untreated WCH or treated WCE and 38 487 with normal BP followed for a mean of 3 to 19 years. Compared with normotension, untreated WCH was associated with an increased risk for cardiovascular events (hazard ratio [HR], 1.36), all-cause mortality (HR, 1.33), and cardiovascular mortality (HR, 2.09); the risk of WCH was attenuated in studies that included stroke in the definition of cardiovascular events (HR, 1.26). No significant increased risk was found with treated WCE. The findings persisted across several sensitivity analyses although are not consistent with several early studies. The analysis supports guidelines recommending out-of-office BP monitoring. Source: https://annals.org/

hyangiu

Recent Posts

Dose Response of Physical Activity in CVD and Mortality

Two recent studies highlight the importance of physical activity volume and intensity in reducing cardiovascular…

1 day ago

Faster Walking Pace May Reduce Risk of Cardiac Arrhythmias

A prospective UK cohort study found that both self-reported average or brisk walking pace and…

1 day ago

4:3 Intermittent Fasting Outperforms Daily Caloric Restriction for Weight Loss

A U.S. randomized clinical trial found that 4:3 intermittent fasting (IMF) led to slightly greater…

4 weeks ago

Comparative CVD Efficacy of Newer Glucose-Lowering Drugs in Elderly T2D Patients

A Danish nationwide cohort study provided real world evidence that both glucagon-like peptide 1 receptor…

1 month ago

Efficacy of Non-Surgical and Non-Interventional Treatments in Low Back Pain

A systematic review and meta-analysis of placebo-controlled randomized trials showed that there is moderate certainty…

1 month ago

Statin Use Linked to Lower Risks of HCC and Liver Disease Progression

A US cohort study indicated that statin use may reduce the risks of hepatocellular carcinoma…

1 month ago

This website uses cookies.